Butler James L, Paulsen Ole
Department of Physiology, Development and Neuroscience, University of Cambridge, Physiological Laboratory, Downing Street, Cambridge CB2 3EG, United Kingdom.
Department of Physiology, Development and Neuroscience, University of Cambridge, Physiological Laboratory, Downing Street, Cambridge CB2 3EG, United Kingdom.
Curr Opin Neurobiol. 2015 Apr;31:40-4. doi: 10.1016/j.conb.2014.07.025. Epub 2014 Aug 17.
Network oscillations are present throughout the mammalian brain. They are important for certain cognitive functions, such as learning and memory. The hippocampus exhibits prominent oscillations similar to those seen in other parts of the cortex. Due to its highly organised lamellar structure, ex vivo and in vitro preparations from the hippocampus have provided experimental models within which to study network oscillations. As such, experiments in hippocampal slices continue to progress our understanding about both the mechanisms and functions of cortical network oscillations. Here, advances from the past two years are summarised, and the current state of the field discussed.
网络振荡存在于整个哺乳动物大脑中。它们对某些认知功能很重要，比如学习和记忆。海马体表现出与在皮质其他部位所见类似的显著振荡。由于其高度有序的层状结构，海马体的离体和体外制备物提供了用于研究网络振荡的实验模型。因此，海马体切片实验不断推进我们对皮质网络振荡的机制和功能的理解。在此，总结过去两年的进展，并讨论该领域的当前状态。
