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蛋白质能量营养不良患者的口服血浆锌耐量试验

Oral plasma zinc tolerance test in patients with protein energy malnutrition.

作者信息

Atalay Y, Arcasoy A, Kürkçüoğlu M

机构信息

Department of Paediatrics, Atatürk University, Erzurum, Turkey.

出版信息

Arch Dis Child. 1989 Nov;64(11):1608-11. doi: 10.1136/adc.64.11.1608.

Abstract

Zinc absorption was measured in 37 children with malnutrition using the oral zinc tolerance test (22.5 mg elementary zinc) and the results compared with those of a group of healthy control subjects. The increase in plasma zinc was significantly lower in patients with marasmic kwashiorkor than in the control group. The zinc tolerance test was, however, normal in marasmic patients. We conclude that zinc deficiency occurs in some types of protein energy malnutrition, and that malabsorption may aggravate zinc deficiency. It is reasonable to give higher doses of zinc than are usually recommended during oral zinc supplementation in patients with protein energy malnutrition.

摘要

采用口服锌耐量试验(22.5毫克元素锌)对37名营养不良儿童的锌吸收情况进行了测量,并将结果与一组健康对照受试者的结果进行了比较。消瘦型夸希奥科病患者血浆锌的升高明显低于对照组。然而,消瘦型患者的锌耐量试验结果正常。我们得出结论,在某些类型的蛋白质能量营养不良中会发生锌缺乏,并且吸收不良可能会加重锌缺乏。对于蛋白质能量营养不良患者,在口服补锌时给予比通常推荐剂量更高的锌剂量是合理的。

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本文引用的文献

4
Tissue zinc levels and zinc excretion during experimental zinc depletion in young men.
Am J Clin Nutr. 1984 Apr;39(4):556-70. doi: 10.1093/ajcn/39.4.556.
6
Skin breakdown in kwashiorkor responds to zinc.夸希奥科病中的皮肤破损对锌有反应。
Lancet. 1980 Jun 7;1(8180):1256. doi: 10.1016/s0140-6736(80)91722-5.
8
Jejunal mucosa in infant malnutrition.婴儿营养不良时的空肠黏膜
Am J Clin Nutr. 1968 Sep;21(9):976-83. doi: 10.1093/ajcn/21.9.976.
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Small intestine in protein malnutrition.
Am J Clin Nutr. 1968 Aug;21(8):813-9. doi: 10.1093/ajcn/21.8.813.

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