Investigaciones en Alergia y Enfermedades Respiratorias- InAER, Buenos Aires, Argentina.
Department of Internal Medicine, Hanyang University Hospital, Seoul, South Korea.
World Allergy Organ J. 2014 May 30;7(1):8. doi: 10.1186/1939-4551-7-8. eCollection 2014.
In the past, asthma was considered mainly as a childhood disease. However, asthma is an important cause of morbidity and mortality in the elderly nowadays. In addition, the burden of asthma is more significant in the elderly than in their younger counterparts, particularly with regard to mortality, hospitalization, medical costs or health-related quality of life. Nevertheless, asthma in the elderly is still been underdiagnosed and undertreated. Therefore, it is an imperative task to recognize our current challenges and to set future directions. This project aims to review the current literature and identify unmet needs in the fields of research and practice for asthma in the elderly. This will enable us to find new research directions, propose new therapeutic strategies, and ultimately improve outcomes for elderly people with asthma. There are data to suggest that asthma in older adults is phenotypically different from young patients, with potential impact on the diagnosis, assessment and management in this population. The diagnosis of AIE in older populations relies on the same clinical findings and diagnostic tests used in younger populations, but the interpretation of the clinical data is more difficult. The challenge today is to encourage new research in AIE but to use the existing knowledge we have to make the diagnosis of AIE, educate the patient, develop a therapeutic approach to control the disease, and ultimately provide a better quality of life to our elderly patients.
在过去,哮喘主要被认为是一种儿童疾病。然而,如今哮喘是老年人发病率和死亡率的一个重要原因。此外,与年轻人相比,哮喘在老年人中的负担更重,特别是在死亡率、住院率、医疗费用或与健康相关的生活质量方面。尽管如此,老年人哮喘仍未得到充分诊断和治疗。因此,认识到我们当前的挑战并确定未来的方向是当务之急。本项目旨在回顾当前的文献,确定老年人哮喘在研究和实践领域的未满足需求。这将使我们能够找到新的研究方向,提出新的治疗策略,并最终改善老年哮喘患者的预后。有数据表明,老年成年人的哮喘表型与年轻患者不同,这可能对该人群的诊断、评估和管理产生影响。老年人群中 AIE 的诊断依赖于与年轻人群相同的临床发现和诊断测试,但临床数据的解释更为困难。今天的挑战是鼓励对 AIE 的新研究,但要利用我们现有的知识来做出 AIE 的诊断,教育患者,制定控制疾病的治疗方法,并最终为我们的老年患者提供更好的生活质量。