Department of Civil and Environmental Engineering, University of Missouri, E2509 Lafferre Hall, Columbia, MO 65211, USA.
Department of Chemical Engineering, Instituto Tecnológico de Buenos Aires, Lavardén 315, Buenos Aires C1437FBG, Argentina.
Molecules. 2021 Oct 15;26(20):6233. doi: 10.3390/molecules26206233.
Molecular imprinted polymers are custom made materials with specific recognition sites for a target molecule. Their specificity and the variety of materials and physical shapes in which they can be fabricated make them ideal components for sensing platforms. Despite their excellent properties, MIP-based sensors have rarely left the academic laboratory environment. This work presents a comprehensive review of recent reports in the environmental and biomedical fields, with a focus on electrochemical and optical signaling mechanisms. The discussion aims to identify knowledge gaps that hinder the translation of MIP-based technology from research laboratories to commercialization.
分子印迹聚合物是具有针对目标分子的特定识别位点的定制材料。它们的特异性以及可以制造它们的材料和物理形状的多样性,使它们成为传感平台的理想组成部分。尽管具有优异的性能,但基于 MIP 的传感器很少离开学术实验室环境。本工作对环境和生物医学领域的最新报告进行了全面综述,重点介绍了电化学和光学信号机制。讨论旨在确定阻碍基于 MIP 的技术从研究实验室转化为商业化的知识差距。