Département de Microbiologie et Immunologie, CHU Sainte-Justine, Université de Montréal, Montréal, Québec H3T 1C5, Canada.
Diagn Microbiol Infect Dis. 2013 Jul;76(3):255-61. doi: 10.1016/j.diagmicrobio.2013.03.008. Epub 2013 Apr 17.
During the last decade, a variety of molecular assays targeting respiratory viruses have been developed and commercialized. Therefore, multiplex PCR are increasingly used in everyday clinical practice. This improves our understanding of respiratory virus epidemiology and enhances our concerns about their clinical impact in specific patient populations. However, questions remain regarding cost-effectiveness of performing these diagnostic tests in routine and their real impact on patient care. This article will review available data and highlight unresolved questions about cost-effectiveness, infection control, clinical utility and public health impact of multiplex respiratory virus assays.
在过去的十年中，已经开发和商业化了多种针对呼吸道病毒的分子检测方法。因此，多重 PCR 越来越多地应用于日常临床实践。这提高了我们对呼吸道病毒流行病学的认识，并使我们更加关注它们在特定患者群体中的临床影响。然而，关于在常规情况下进行这些诊断测试的成本效益及其对患者护理的实际影响，仍存在一些问题。本文将回顾现有数据，并强调关于多重呼吸道病毒检测的成本效益、感染控制、临床实用性和公共卫生影响的未解决问题。
