瑞典接触性皮炎研究小组进行的一项多中心研究：用两种浓度的纺织染料混合物进行斑贴试验。
Patch testing with a textile dye mix in two concentrations - a multicentre study by the Swedish contact dermatitis research group.
作者信息
Ryberg Kristina, Bråred-Christensson Johanna, Engfeldt Malin, Isaksson Marléne, Lindberg Magnus, Matura Mihaly, Stenberg Berndt, Svedman Cecilia, Bruze Magnus
机构信息
Department of Dermatology, Uddevalla Hospital, SE-451 80 Uddevalla, Sweden.
出版信息
Acta Derm Venereol. 2015 Apr;95(4):427-31. doi: 10.2340/00015555-1956.
UNLABELLED
Disperse dyes, which are used for colouring synthetic textile fibres, are well-known contact sensitisers. To investigate the outcome of patch-testing with a textile dye mix (TDM) at 7 dermatology clinics in Sweden, a TDM tested at 2 concentrations was included into the baseline series during one year. The mix consisted of Disperse (D) Blue 35, D Yellow 3, D Orange 1 and 3, D Red 1 and 17, all 1.0%, and D Blue 106 and D Blue 124, each 0.3% in the mix 6.6% and 1.0% each in the mix 8.0%. In 2,122 tested patients, contact allergy to the TDM at the concentration 8.0% was found in 2.8% and to the TDM at 6.6% in 2.5% of the patients. The contact allergy to the TDM could explain or contribute to the dermatitis in about 35% of the patients.
CONCLUSION
contact allergy to the TDM is common and inclusion into the Swedish baseline series should be considered.
未标注
用于合成纺织纤维染色的分散染料是众所周知的接触性致敏剂。为了调查瑞典7家皮肤科诊所使用纺织品染料混合物（TDM）进行斑贴试验的结果，在一年期间，将两种浓度的TDM纳入基线系列。该混合物由分散蓝35、分散黄3、分散橙1和3、分散红1和17组成，各占1.0%，分散蓝106和分散蓝124在混合物中各占0.3%，在混合物8.0%中各占6.6%和1.0%。在2122名受试患者中，发现2.8%的患者对浓度为8.0%的TDM有接触性过敏，2.5%的患者对浓度为6.6%的TDM有接触性过敏。对TDM的接触性过敏可解释或导致约35%的患者发生皮炎。
结论
对TDM的接触性过敏很常见，应考虑将其纳入瑞典基线系列。
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