Department of Occupational and Environmental Dermatology, Lund University, Malmö University Hospital, Malmö, Sweden.
Dermatitis. 2010 Jan-Feb;21(1):49-56.
Among the textile dyes, disperse dyes are common sensitizers.
To investigate whether patch testing with a textile dye mix consisting of eight disperse dyes would be equivalent to testing with the separate ingredients of the mix at the concentrations used in the mix.
Researchers tested 1,780 consecutive patients with a mix consisting of Disperse Blue 35, Disperse Yellow 3, Disperse Orange 1, Disperse Orange 31 (mislabeled as Disperse Orange 3), Disperse Red 1 and 17, all at 0.5%, and Disperse Blue 106 and 124, both at 0.1%, and with the ingredients at these concentrations. Testing with the labeled dyes at 1.0% was done on 500 of the patients and additionally on the remaining patients who reacted positively to the mix, any of the ingredients, p-phenylenediamine, or black rubber mix.
Thirty-five patients (2%) reacted to the mix, and 34 patients were allergic to at least one ingredient tested at the lower concentration.
The textile dye mix was as good a detector of contact allergy to the disperse dyes as was testing with any combination of the ingredients at the concentration in the mix. Increasing the concentration of the ingredients of the textile dye mix might increase the sensitivity of the mix.
在纺织染料中，分散染料是常见的致敏剂。
研究用包含八种分散染料的纺织染料混合物进行斑贴试验是否等同于用混合物中使用的浓度的混合物的单独成分进行测试。
研究人员用包含分散蓝 35、分散黄 3、分散橙 1、分散橙 31（误标为分散橙 3）、分散红 1 和 17，均为 0.5%，以及分散蓝 106 和 124，均为 0.1%的混合物，以及这些浓度的成分，对 1780 例连续患者进行了测试。对 500 名患者进行了用标记染料进行 1.0%的测试，对混合组、任何一种成分、对苯二胺或黑色橡胶混合物阳性反应的剩余患者也进行了测试。
35 名患者（2%）对混合物有反应，34 名患者对低浓度测试的至少一种成分过敏。
与用混合物中使用的浓度的混合物的任何成分组合进行测试相比，纺织染料混合物对分散染料的接触过敏具有更好的检测效果。增加纺织染料混合物成分的浓度可能会提高混合物的敏感性。
