Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji.
Department of Ophthalmology, The University of Tokyo, Tokyo.
J Glaucoma. 2019 Feb;28(2):172-177. doi: 10.1097/IJG.0000000000001138.
We evaluated the agreement between the intraocular pressure (IOP) values of new rebound tonometer, Icare ic100, and Icare TA01i or Goldmann applanation tonometer (GAT).
We studied one eye each of 106 subjects (57 with primary open-angle glaucoma, 49 healthy subjects). IOP was randomly measured twice with the patient in sitting position using the Icare ic100, Icare TA01i, and GAT. Tonometer measurements were evaluated using Bland-Altman analysis. The relationship between IOP difference (Icare ic100-GAT) and age, sex, disease, axial length, central corneal thickness (CCT), and corneal curvature was investigated using multivariate regression analysis.
IOPs measured using Icare ic100, Icare TA01i, and GAT were 11.7±3.0 (mean±standard deviation), 12.2±2.9, and 16.0±3.2 mm Hg, respectively (P<0.001, one-way analysis of variance). Icare ic100 showed significantly lower IOPs than GAT (P<0.05), but not than Icare TA01 (P>0.05; Tukey-Kramer test). Bland-Altman analysis revealed that the mean differences between Icare ic100 and Icare TA01i and those between Icare ic100 and GAT were -0.46 and -4.2 mm Hg, respectively (95% limits of agreement, -3.35 to 2.42 and -10.10 to 1.61 mm Hg, respectively). For IOP differences between Icare ic100 and GAT, parameters selected in the optimal model were CCT (coefficient, 20.3, P=0.029), corneal curvature (3.0, P=0.020), and glaucoma-normal (-1.0, P=0.004).
The new rebound tonometer Icare ic100 almost constantly showed IOPs lower than GAT. The difference was affected by CCT, corneal curvature, and disease.
评估新型回弹眼压计 Icare ic100 与 Icare TA01i 或 Goldmann 压平眼压计（GAT）的眼压（IOP）值之间的一致性。
我们对 106 名受试者（57 名原发性开角型青光眼患者，49 名健康受试者）的每只眼睛进行了研究。IOP 随机使用 Icare ic100、Icare TA01i 和 GAT 在坐位下测量两次。采用 Bland-Altman 分析评估眼压计测量值。采用多元回归分析研究 IOP 差值（Icare ic100-GAT）与年龄、性别、疾病、眼轴长度、中央角膜厚度（CCT）和角膜曲率之间的关系。
使用 Icare ic100、Icare TA01i 和 GAT 测量的 IOP 分别为 11.7±3.0（平均值±标准差）、12.2±2.9 和 16.0±3.2mmHg（P<0.001，单因素方差分析）。Icare ic100 测量的 IOP 明显低于 GAT（P<0.05），但与 Icare TA01i 相比无差异（P>0.05；Tukey-Kramer 检验）。Bland-Altman 分析显示，Icare ic100 与 Icare TA01i 之间以及 Icare ic100 与 GAT 之间的平均差异分别为-0.46mmHg 和-4.2mmHg（95%一致性限分别为-3.35 至 2.42mmHg 和-10.10 至 1.61mmHg）。对于 Icare ic100 与 GAT 之间的 IOP 差值，最佳模型中选择的参数为 CCT（系数，20.3，P=0.029）、角膜曲率（3.0，P=0.020）和青光眼-正常（-1.0，P=0.004）。
新型回弹眼压计 Icare ic100 几乎始终显示出低于 GAT 的 IOP。差异受 CCT、角膜曲率和疾病的影响。
