Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Acta Ophthalmol. 2013 Aug;91(5):e392-6. doi: 10.1111/aos.12109. Epub 2013 Mar 25.
To evaluate the clinical usefulness of a new rebound tonometer, Icare(®) PRO (Icare PRO), by comparison with Goldmann applanation tonometry (GAT) in a study on patients with glaucoma.
One hundred and seventy-two eyes of 86 subjects were enrolled in this study. All of the subjects were examined with an autorefractometer, Icare PRO, slit-lamp biomicroscope, GAT, ultrasound A-scan and pachymeter. Three intraocular pressure (IOP) measurements were obtained by Icare PRO and GAT. The intraobserver reliabilities were established by calculating the intraclass correlation coefficients. The Bland-Altman plot was used to compare the Icare PRO and GAT.
There was a good correlation between the IOP measurement by GAT and that by Icare PRO (r = 0.6995, p < 0.001). The intraclass correlation coefficients of Icare PRO and GAT were 0.778 and 0.955, respectively. The IOP differences between Icare PRO and GAT (mean: 1.92 mmHg; SD: 3.29 mmHg; 95% limit of agreement: -4.52 to 8.37 mmHg) did not vary over the wide range of central corneal thickness (p = 0.498), age (p = 0.248), axial length (p = 0.277) or spherical equivalent (p = 0.075).
Although IOP with Icare PRO was higher than that with GAT, especially at lower GAT IOP value, Icare PRO was found to be a reliable method and showed a good correlation with GAT. The IOP difference between Icare PRO and GAT was not affected by the central corneal thickness, age, axial length or spherical equivalent. Icare PRO can be expected not only to be a good screening tool but also to be a good substitute for GAT.
通过与 Goldmann 压平眼压计(GAT)的比较,评估新型回弹眼压计 Icare(®) PRO(Icare PRO)在青光眼患者中的临床应用价值。
本研究纳入了 86 例患者的 172 只眼。所有患者均接受自动验光仪、Icare PRO、裂隙灯生物显微镜、GAT、超声 A 扫描和角膜测厚仪检查。通过 Icare PRO 和 GAT 获得 3 次眼压测量值。采用组内相关系数评估观察者内可信度。采用 Bland-Altman 图比较 Icare PRO 和 GAT。
GAT 测量的眼压与 Icare PRO 测量的眼压之间存在良好的相关性(r = 0.6995,p < 0.001)。Icare PRO 和 GAT 的组内相关系数分别为 0.778 和 0.955。Icare PRO 与 GAT 的眼压差值(平均值:1.92 mmHg;标准差:3.29 mmHg;95%一致性界限:-4.52 至 8.37 mmHg)在较宽的中央角膜厚度范围内(p = 0.498)、年龄范围内(p = 0.248)、眼轴长度范围内(p = 0.277)或等效球镜范围内(p = 0.075)均无差异。
尽管 Icare PRO 测量的眼压值高于 GAT,尤其是在较低的 GAT 眼压值时,但 Icare PRO 被认为是一种可靠的方法,与 GAT 具有良好的相关性。Icare PRO 与 GAT 的眼压差值不受中央角膜厚度、年龄、眼轴长度或等效球镜的影响。Icare PRO 不仅有望成为一种良好的筛查工具,还可能成为 GAT 的良好替代品。