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洋甘菊茶对 2 型糖尿病患者血糖控制和血脂谱的影响。

Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes.

机构信息

Department of Nutrition in Community, Faculty of Nutrition, Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Students' Research Committee, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Endocrinol Invest. 2015 Feb;38(2):163-70. doi: 10.1007/s40618-014-0170-x. Epub 2014 Sep 7.

Abstract

AIMS

This study aimed at assessing the effects of chamomile tea consumption on glycemic control and serum lipid profile in patients with type 2 diabetes mellitus (T2DM).

METHODS

This single-blind randomized controlled clinical trial was conducted on 64 individuals with T2DM (males and females) aged between 30 and 60 years. The intervention group (n = 32) consumed chamomile tea (3 g/150 mL hot water) three times per day immediately after meals for 8 weeks. The control group (n = 32) followed a water regimen for the same intervention period. Fasting blood samples, anthropometric measurements, and 3-day, 24-h dietary recalls were collected at the baseline and at the end of the trial. Data were analyzed by independent t test, paired t test, Pearson correlation test, and analysis of covariance.

RESULTS

Chamomile tea significantly decreased concentration of HbA1C (p = 0.03), serum insulin levels (p < 0.001), homeostatic model assessment for insulin resistance (p < 0.001), total cholesterol (p = 0.001), triglyceride (p < 0.001), and low-density lipoprotein cholesterol (p = 0.05) compared with control group. No significant changes were shown in serum high-density lipoprotein cholesterol levels in both groups.

CONCLUSION

Chamomile tea has some beneficial effects on glycemic control and serum lipid profile in T2DM patients.

摘要

目的

本研究旨在评估饮用甘菊茶对 2 型糖尿病(T2DM)患者血糖控制和血清血脂谱的影响。

方法

这是一项单盲随机对照临床试验,共纳入 64 名年龄在 30 至 60 岁之间的 T2DM 患者(男性和女性)。干预组(n=32)每天饭后立即饮用三次甘菊茶(3 克/150 毫升热水),共 8 周。对照组(n=32)在相同的干预期间遵循水疗方案。在基线和试验结束时采集空腹血样、人体测量学测量值和 3 天 24 小时膳食回忆。采用独立 t 检验、配对 t 检验、皮尔逊相关检验和协方差分析对数据进行分析。

结果

与对照组相比,甘菊茶显著降低了 HbA1C(p=0.03)、血清胰岛素水平(p<0.001)、胰岛素抵抗评估的稳态模型(HOMA-IR)(p<0.001)、总胆固醇(p=0.001)、甘油三酯(p<0.001)和低密度脂蛋白胆固醇(p=0.05)的浓度。两组患者的血清高密度脂蛋白胆固醇水平均无显著变化。

结论

甘菊茶对 T2DM 患者的血糖控制和血清血脂谱有一定的有益影响。

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