患者导向湿疹量表与患者导向特应性皮炎评分与湿疹面积和严重程度指数及其他特应性皮炎衡量指标的比较：验证研究。
Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: A validation study.
机构信息
Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.
Department of Dermatology, Feinberg School of Medicine at Northwestern University, Chicago, Illinois.
出版信息
Ann Allergy Asthma Immunol. 2020 Jul;125(1):78-83. doi: 10.1016/j.anai.2020.03.006. Epub 2020 Mar 18.
BACKGROUND
Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with atopic dermatitis (AD). Even less is known about how PO-SCORAD performs compared with the Patient-Oriented Eczema Measure (POEM).
OBJECTIVE
To examine the measurement properties of PO-SCORAD and compare them with those of POEM.
METHODS
A prospective dermatology practice-based study of 291 patients with AD (age range, 18-72 years).
RESULTS
PO-SCORAD and POEM were moderately correlated with each other (Spearman ρ = 0.56) and had weak-moderate correlations with the Numeric Rating Scale (NRS) worst itch and average itch, Dermatology Life Quality Index (DLQI), ItchyQOL, Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance (SD) and Sleep-Related Impairment (SRI), Patient Health Questionnaire-9 (PHQ-9), and Eczema Area and Severity Index (EASI) (P < .001). POEM had significantly stronger correlations with DLQI, ItchyQOL, and EASI than did PO-SCORAD. PO-SCORAD and POEM had fair discriminant validity. Changes from baseline in PO-SCORAD and POEM were moderately correlated with each other; were weakly to strongly correlated with NRS worst itch and average itch, DLQI, ItchyQOL, PROMIS SD, PROMIS SRI, PHQ-9, and EASI; and had good test-retest reliability. There was no differential item functioning of items or floor or ceiling effects for PO-SCORAD or POEM. The thresholds for meaningful change for PO-SCORAD and POEM were -15.5 and -5.0, respectively. Median completion times for PO-SCORAD and POEM were 3 minutes and 1 minute, respectively.
CONCLUSION
PO-SCORAD and POEM had good construct and cross-cultural validity, reliability, and responsiveness in adults with AD and were feasible for use in clinical trials and practice. However, POEM had better measurement properties than PO-SCORAD.
背景
对于特应性皮炎（AD）患者，有关患者导向的特应性皮炎评分（PO-SCORAD）的测量特性的了解甚少。与患者导向的湿疹量表（POEM）相比，PO-SCORAD 的表现如何，这方面的了解就更少了。
目的
检验 PO-SCORAD 的测量特性，并将其与 POEM 进行比较。
方法
一项前瞻性、基于皮肤科实践的研究纳入了 291 例 AD 患者（年龄 18-72 岁）。
结果
PO-SCORAD 与 POEM 中度相关（Spearman ρ=0.56），与数字评分量表（NRS）最差瘙痒和平均瘙痒、皮肤病生活质量指数（DLQI）、瘙痒 QOL 量表、患者报告结局测量信息系统（PROMIS）睡眠障碍（SD）和睡眠相关损伤（SRI）、患者健康问卷-9（PHQ-9）和湿疹面积及严重程度指数（EASI）也有弱-中度相关性（P<0.001）。POEM 与 DLQI、ItchyQOL 和 EASI 的相关性均显著强于 PO-SCORAD。PO-SCORAD 和 POEM 具有良好的判别有效性。与基线相比，PO-SCORAD 和 POEM 的变化彼此中度相关；与 NRS 最差瘙痒和平均瘙痒、DLQI、ItchyQOL、PROMIS SD、PROMIS SRI、PHQ-9 和 EASI 也有弱-强相关性；且具有良好的测试重测信度。PO-SCORAD 和 POEM 均不存在项目的区分度功能障碍或地板或天花板效应。PO-SCORAD 和 POEM 的有意义变化阈值分别为-15.5 和-5.0。PO-SCORAD 和 POEM 的中位数完成时间分别为 3 分钟和 1 分钟。
结论
PO-SCORAD 和 POEM 在 AD 成人中具有良好的结构效度、跨文化效度、信度和反应度，并且在临床试验和实践中是可行的。然而，POEM 的测量特性优于 PO-SCORAD。
Zotero 插件