Karbassi Elika, Asadinezhad Ahmad, Lehocký Marian, Humpolíček Petr, Vesel Alenka, Novák Igor, Sáha Petr
Department of Chemical Engineering, Isfahan University of Technology, Esfahan 84156-83111, Iran.
Centre of Polymer Systems, Tomas Bata University in Zlín, Zlín 76001, Czech Republic.
Int J Mol Sci. 2014 Aug 21;15(8):14684-96. doi: 10.3390/ijms150814684.
Alginic acid coated polyethylene films were examined in terms of surface properties and bacteriostatic performance against two most representative bacterial strains, that is, Escherichia coli and Staphylococcus aureus. Microwave plasma treatment followed by brush formation in vapor state from three distinguished precursors (allylalcohol, allylamine, hydroxyethyl methacrylate) was carried out to deposit alginic acid on the substrate. Surface analyses via various techniques established that alginic acid was immobilized onto the surface where grafting (brush) chemistry influenced the amount of alginic acid coated. Moreover, alginic acid was found to be capable of bacterial growth inhibition which itself was significantly affected by the brush type. The polyanionic character of alginic acid as a carbohydrate polymer was assumed to play the pivotal role in antibacterial activity. The cell wall composition of two bacterial strains along with the substrates physicochemical properties accounted for different levels of bacteriostatic performance.
对藻酸包覆的聚乙烯薄膜进行了表面性能以及针对两种最具代表性的细菌菌株（即大肠杆菌和金黄色葡萄球菌）的抑菌性能研究。通过微波等离子体处理，然后从三种不同的前驱体（烯丙醇、烯丙胺、甲基丙烯酸羟乙酯）以气态形成刷状结构，将藻酸沉积在基底上。通过各种技术进行的表面分析表明，藻酸固定在表面上，接枝（刷状）化学影响了藻酸的包覆量。此外，发现藻酸能够抑制细菌生长，而其本身受到刷状类型的显著影响。藻酸作为一种碳水化合物聚合物的聚阴离子特性被认为在抗菌活性中起关键作用。两种细菌菌株的细胞壁组成以及基底的物理化学性质导致了不同水平的抑菌性能。
