Heeren T F C, Krüger E, Holz F G, Charbel Issa P
Universitäts-Augenklinik Bonn, Ernst-Abbe-Str. 2, 53127, Bonn, Deutschland.
Ophthalmologe. 2014 Sep;111(9):829-33. doi: 10.1007/s00347-014-3083-3.
The first symptoms of macular telangiectasia type 2 usually occur between 50 and 70 years of age. Functional alterations topographically correspond to the morphological changes. Characteristic paracentral scotomata due to focal photoreceptor atrophy can be detected using microperimetry. The predominant paracentral functional loss may cause reading difficulties despite visual acuity in the range between 20/20 and 20/50. Visual acuity around 20/200 may occur once the paracentral photoreceptor atrophy extends centrally, or due to the development of a macular hole or a secondary neovascular membrane. Progression of functional loss can often only be detected by mapping scotoma size or occurrence using microperimetry, while visual acuity may remain unchanged.
2型黄斑毛细血管扩张症的首发症状通常出现在50至70岁之间。功能改变在地形学上与形态学变化相对应。使用微视野计可检测到由于局灶性光感受器萎缩导致的特征性旁中心暗点。尽管视力在20/20至20/50之间，但主要的旁中心功能丧失可能会导致阅读困难。一旦旁中心光感受器萎缩向中心扩展，或者由于黄斑裂孔或继发性新生血管膜的形成，视力可能会降至20/200左右。功能丧失的进展通常只能通过使用微视野计绘制暗点大小或出现情况来检测，而视力可能保持不变。
