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屎肠球菌 DSM 10663 NCIMB 10415 口服菌株对哺乳仔猪腹泻模式和生产性能的影响。

Effects of oral Enterococcus faecium strain DSM 10663 NCIMB 10415 on diarrhoea patterns and performance of sucking piglets.

机构信息

Chair of Nutrition Physiology and Animal Nutrition, Faculty of Agricultural and Environmental Sciences, University of Rostock, Justus-von-Liebig-Weg 8, 18059 Rostock, Germany.

Department of Animal Nutrition, Institute for Agricultural and Nutritional Sciences, Martin-Luther-University Halle-Wittenberg, Theodor-Lieser-Str. 11, 06120 Halle (Saale), Germany.

出版信息

Benef Microbes. 2015 Mar;6(1):41-4. doi: 10.3920/BM2014.0008.

Abstract

Effects of probiotic Enterococcus faecium DMS 10663 NCIMB 10415 on diarrhoea and performance of sucking piglets were evaluated in a double-blind, placebo-controlled study. Piglets from treatment group (TG, n=56) and placebo group (PG, n=53) sows were included in the study. Immediately after birth and at day 2 and 3 post natum, each of the TG piglets received 2.8×10(9) colony forming units (cfu) per os. From day 4 until weaning (day 26), 1.26×10(9) cfu E. faecium/piglet were given twice a day via a liquid additive. Piglets already suffering from diarrhoea additionally got a glucose-electrolyte solution enriched with 2.9×10(8) (week 1) and 5.8×10(8) (week 2) cfu E. faecium/day. PG piglets received corresponding placebo preparations. A score was defined to characterise the severity of diarrhoea, including accompanying symptoms. The counts of viable born, stillborn and weaned piglets were similar in TG and PG litters (P>0.05). The probiotic treatment mitigated incidence and severity of diarrhoea (P<0.05) with no impact on diarrhoea length (P>0.05). Probiotic treatment improved daily weight gain (P<0.05) yet with no provable effect on body weight at weaning (P>0.05). The additional supply of E. faecium in piglets suffering from diarrhoea had no further beneficial effect.

摘要

在一项双盲、安慰剂对照研究中,评估了益生菌粪肠球菌 DMS 10663 NCIMB 10415 对仔猪腹泻和生产性能的影响。将来自处理组(TG,n=56)和安慰剂组(PG,n=53)母猪的仔猪纳入研究。TG 仔猪在出生后立即和出生后第 2 天和第 3 天,每头口服 2.8×10(9)个菌落形成单位(cfu)。从第 4 天到断奶(第 26 天),每天通过液体添加剂给予 1.26×10(9)cfu 粪肠球菌/仔猪两次。已经患有腹泻的仔猪另外还接受了富含 2.9×10(8)cfu(第 1 周)和 5.8×10(8)cfu(第 2 周)的葡萄糖电解质溶液。PG 仔猪接受相应的安慰剂制剂。定义了一个评分来描述腹泻的严重程度,包括伴随的症状。TG 和 PG 窝产仔中活产仔、死产仔和断奶仔的数量相似(P>0.05)。益生菌治疗减轻了腹泻的发生率和严重程度(P<0.05),但对腹泻持续时间没有影响(P>0.05)。益生菌治疗改善了日增重(P<0.05),但对断奶时的体重没有可证明的影响(P>0.05)。在患有腹泻的仔猪中额外供应粪肠球菌没有进一步的有益效果。

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