Chair of Nutrition Physiology and Animal Nutrition, Faculty of Agricultural and Environmental Sciences, University of Rostock, Justus-von-Liebig-Weg 8, 18059 Rostock, Germany.
Department of Animal Nutrition, Institute for Agricultural and Nutritional Sciences, Martin-Luther-University Halle-Wittenberg, Theodor-Lieser-Str. 11, 06120 Halle (Saale), Germany.
Benef Microbes. 2015 Mar;6(1):41-4. doi: 10.3920/BM2014.0008.
Effects of probiotic Enterococcus faecium DMS 10663 NCIMB 10415 on diarrhoea and performance of sucking piglets were evaluated in a double-blind, placebo-controlled study. Piglets from treatment group (TG, n=56) and placebo group (PG, n=53) sows were included in the study. Immediately after birth and at day 2 and 3 post natum, each of the TG piglets received 2.8×10(9) colony forming units (cfu) per os. From day 4 until weaning (day 26), 1.26×10(9) cfu E. faecium/piglet were given twice a day via a liquid additive. Piglets already suffering from diarrhoea additionally got a glucose-electrolyte solution enriched with 2.9×10(8) (week 1) and 5.8×10(8) (week 2) cfu E. faecium/day. PG piglets received corresponding placebo preparations. A score was defined to characterise the severity of diarrhoea, including accompanying symptoms. The counts of viable born, stillborn and weaned piglets were similar in TG and PG litters (P>0.05). The probiotic treatment mitigated incidence and severity of diarrhoea (P<0.05) with no impact on diarrhoea length (P>0.05). Probiotic treatment improved daily weight gain (P<0.05) yet with no provable effect on body weight at weaning (P>0.05). The additional supply of E. faecium in piglets suffering from diarrhoea had no further beneficial effect.
在一项双盲、安慰剂对照研究中,评估了益生菌粪肠球菌 DMS 10663 NCIMB 10415 对仔猪腹泻和生产性能的影响。将来自处理组(TG,n=56)和安慰剂组(PG,n=53)母猪的仔猪纳入研究。TG 仔猪在出生后立即和出生后第 2 天和第 3 天,每头口服 2.8×10(9)个菌落形成单位(cfu)。从第 4 天到断奶(第 26 天),每天通过液体添加剂给予 1.26×10(9)cfu 粪肠球菌/仔猪两次。已经患有腹泻的仔猪另外还接受了富含 2.9×10(8)cfu(第 1 周)和 5.8×10(8)cfu(第 2 周)的葡萄糖电解质溶液。PG 仔猪接受相应的安慰剂制剂。定义了一个评分来描述腹泻的严重程度,包括伴随的症状。TG 和 PG 窝产仔中活产仔、死产仔和断奶仔的数量相似(P>0.05)。益生菌治疗减轻了腹泻的发生率和严重程度(P<0.05),但对腹泻持续时间没有影响(P>0.05)。益生菌治疗改善了日增重(P<0.05),但对断奶时的体重没有可证明的影响(P>0.05)。在患有腹泻的仔猪中额外供应粪肠球菌没有进一步的有益效果。