Department of Psychiatry, Seoul Saint Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea.
J Behav Addict. 2014 Mar;3(1):12-20. doi: 10.1556/JBA.3.2014.1.2. Epub 2014 Mar 24.
Evidences indicate that Internet addiction disorder (IAD) has a higher risk of developing aggression and violent behavior. A few correlation studies between IAD and aggression have implicated a common biological mechanism. However, neurobiological approaches to IAD and aggression have not yet been studied.
A literature search for studies for Internet addiction disorder or aggression was performed in the PubMed database and we selected articles about neurobiology of IAD or aggression.
This review includes (a) common neural substrates such as the prefrontal cortex and the limbic system between aggression and IAD; (b) common neuromodulators such as dopamine, norepinephrine, serotonin, opiate and nicotine between aggression and IAD.
Through reviewing the relevant literature, we suggested the possibility of common neurobiology between the two psychiatric phenomena and direction of research on aggression in IAD.
有证据表明，网络成瘾障碍（IAD）有更高的风险发展为攻击性和暴力行为。一些关于 IAD 和攻击性的相关性研究表明存在共同的生物学机制。然而，IAD 和攻击性的神经生物学方法尚未得到研究。
在 PubMed 数据库中对网络成瘾障碍或攻击性的研究进行了文献检索，我们选择了关于 IAD 或攻击性神经生物学的文章。
本综述包括（a）攻击性和 IAD 之间的共同神经基质，如前额叶皮层和边缘系统；（b）攻击性和 IAD 之间的共同神经调质，如多巴胺、去甲肾上腺素、血清素、阿片类和尼古丁。
通过回顾相关文献，我们提出了这两种精神现象之间存在共同神经生物学的可能性，并对 IAD 中的攻击性研究方向提出了建议。
