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A partial pathway- and network-based transformation reveals the synergistic mechanism of JA and UA against cerebral ischemia-reperfusion injury.

作者信息

Guo Shanshan, Guo Li, Yu Yanan, Li Bing, Zhang Yingying, Li Haixia, Wu Ping, Wang Jie, Yuan Ye, Wang Zhong, Wang Yongyan

机构信息

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.

出版信息

Protein Cell. 2014 Nov;5(11):873-7. doi: 10.1007/s13238-014-0098-0.

DOI:10.1007/s13238-014-0098-0
PMID:25217044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4225461/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50de/4235835/361f137dbe42/13238_2014_98_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50de/4235835/af959a802250/13238_2014_98_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50de/4235835/361f137dbe42/13238_2014_98_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50de/4235835/af959a802250/13238_2014_98_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50de/4235835/361f137dbe42/13238_2014_98_Fig2_HTML.jpg

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Front Pharmacol. 2019 Dec 12;10:1383. doi: 10.3389/fphar.2019.01383. eCollection 2019.

本文引用的文献

1
Anti-inflammatory IL-10 is upregulated in both hemispheres after experimental ischemic stroke: Hypertension blunts the response.实验性缺血性中风后，抗炎性白细胞介素-10在双侧大脑半球均上调：高血压会减弱这种反应。
Exp Transl Stroke Med. 2013 Nov 13;5(1):12. doi: 10.1186/2040-7378-5-12.
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Proinflammatory cytokines in the embolic model of cerebral ischemia in rat.大鼠脑缺血栓塞模型中的促炎细胞因子
Iran J Allergy Asthma Immunol. 2014 Apr;13(2):125-30.
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Resveratrol prevents global cerebral ischemia-induced decrease in lipid content.白藜芦醇可预防全脑缺血诱导的脂质含量降低。
Neurol Res. 2013 Jan;35(1):59-64. doi: 10.1179/1743132812Y.0000000116.
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Chapter 5: Network biology approach to complex diseases.第五章：复杂疾病的网络生物学方法。
PLoS Comput Biol. 2012;8(12):e1002820. doi: 10.1371/journal.pcbi.1002820. Epub 2012 Dec 27.
5
Synergistic mechanism of gene expression and pathways between jasminoidin and ursodeoxycholic acid in treating focal cerebral ischemia-reperfusion injury.栀子苷与熊去氧胆酸治疗局灶性脑缺血再灌注损伤的基因表达及通路协同机制。
CNS Neurosci Ther. 2012 Aug;18(8):674-82. doi: 10.1111/j.1755-5949.2012.00348.x. Epub 2012 Jun 22.
6
Chinese medicine injection qingkailing for treatment of acute ischemia stroke: a systematic review of randomized controlled trials.中药注射液清开灵治疗急性缺血性脑卒中的系统评价：随机对照试验研究。
Evid Based Complement Alternat Med. 2012;2012:213172. doi: 10.1155/2012/213172. Epub 2012 May 22.
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Network target for screening synergistic drug combinations with application to traditional Chinese medicine.用于筛选协同药物组合的网络靶点及其在中药中的应用
BMC Syst Biol. 2011 Jun 20;5 Suppl 1(Suppl 1):S10. doi: 10.1186/1752-0509-5-S1-S10.
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Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood.短暂性脑缺血发作样短暂性脑缺血模拟人类外周血基因表达调控。
J Cereb Blood Flow Metab. 2010 Jan;30(1):110-8. doi: 10.1038/jcbfm.2009.189. Epub 2009 Sep 9.
9
Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspects.白细胞介素-6在脑缺血中的矛盾作用：炎症与神经营养作用
J Cereb Blood Flow Metab. 2009 Mar;29(3):464-79. doi: 10.1038/jcbfm.2008.141. Epub 2008 Nov 19.
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Neuroscience. 2009 Feb 6;158(3):1021-9. doi: 10.1016/j.neuroscience.2008.06.052. Epub 2008 Jul 3.