Louis Asa, Peterson Brianna L, Couper Fiona J
Toxicology Laboratory Division, Washington State Patrol, 2203 Airport Way South, Suite 360, Seattle, WA 98134, USA
Toxicology Laboratory Division, Washington State Patrol, 2203 Airport Way South, Suite 360, Seattle, WA 98134, USA.
J Anal Toxicol. 2014 Oct;38(8):563-8. doi: 10.1093/jat/bku067.
The case reports for 18 driving cases positive for the synthetic cannabinoid substances XLR-11 and/or UR-144 are discussed. Eleven of these cases had drug recognition expert evaluations performed. Slurred speech, lack of convergence and body and eyelid tremors were the most consistently noted interview characteristic. Pulse and blood pressure of the subjects were within the expected range. Most of the drivers contacted demonstrated poor driving; however, their performance on the standardized field sobriety tests yielded inconsistent diagnostic information. All cases were negative for other commonly detected drugs that affect the central nervous system, although one case was additionally positive for other synthetic cannabinoids. Of the studied cases, six were positive for only UR-144, whereas eight contained only XLR-11. Four cases were found to have both.
讨论了18例对合成大麻素物质XLR-11和/或UR-144呈阳性的驾驶案例报告。其中11例进行了药物识别专家评估。言语不清、缺乏辐辏以及身体和眼睑震颤是最常被提及的面谈特征。受试者的脉搏和血压在预期范围内。大多数接受接触的驾驶员表现出驾驶能力差;然而,他们在标准化现场清醒度测试中的表现产生了不一致的诊断信息。所有案例对其他常见的影响中枢神经系统的药物检测均为阴性,尽管有一例对其他合成大麻素呈阳性。在所研究的案例中,6例仅对UR-144呈阳性,而8例仅含有XLR-11。发现4例同时含有这两种物质。