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华盛顿州涉嫌酒驾案件中大麻的流行情况。

The prevalence of marijuana in suspected impaired driving cases in Washington state.

作者信息

Couper Fiona J, Peterson Brianna L

机构信息

Toxicology Laboratory Division, Washington State Patrol, 2203 Airport Way S., Suite 360, Seattle, WA 98134, USA

Toxicology Laboratory Division, Washington State Patrol, 2203 Airport Way S., Suite 360, Seattle, WA 98134, USA.

出版信息

J Anal Toxicol. 2014 Oct;38(8):569-74. doi: 10.1093/jat/bku090.

Abstract

In December 2012, the possession and private use of limited quantities of marijuana and marijuana products became legal in the state of Washington. At the same time, the state's driving under the influence statutes were amended to include a per se level of 5 ng/mL delta(9)-tetrahydrocannabinol (THC) in whole blood for drivers aged 21 years and older. The aim of this study was to assess the effect of marijuana legalization on the prevalence of marijuana in suspected impaired driving cases. The prevalence of both active THC and its metabolite carboxy-THC detected in such cases pre-legalization was compared with the prevalence post-legalization. In 2009-2012, the average yearly percentage of cases positive for THC and carboxy-THC was 19.1% (range: 18.2-20.2%) and 27.9% (range: 26.3-28.6%), respectively. In 2013, the percentages had significantly increased to 24.9 and 40.0%, respectively (P < 0.05). The median THC concentration over the 5-year period ranged from 5.2 to 6.3 ng/mL, with individual concentrations ranging up to 90 ng/mL. An average of 56% of cases were at or >5 ng/mL over the 5-year period. The prevalence of alcohol and the majority of other drugs in this same population of suspected impaired drivers submitted for testing did not change during this same 5-year period-marijuana was the only drug to show such an increase in frequency. Further, this observed increase remained after the data had been normalized to account for changes in laboratory testing procedures that occurred during this time period. Future studies need be conducted to ascertain whether the observed increase has had any effect on the incidence of crashes, serious injuries and/or traffic fatalities.

摘要

2012年12月,在华盛顿州,持有和私自使用少量大麻及大麻制品合法化。与此同时,该州对酒驾法规进行了修订,将21岁及以上驾驶者全血中δ⁹-四氢大麻酚(THC)的法定浓度设定为5纳克/毫升。本研究的目的是评估大麻合法化对涉嫌酒驾案件中大麻流行率的影响。将大麻合法化之前此类案件中检测到的活性THC及其代谢物羧基-THC的流行率与合法化之后的流行率进行比较。在2009 - 2012年期间,THC和羧基-THC呈阳性的案件年均百分比分别为19.1%(范围:18.2 - 20.2%)和27.9%(范围:26.3 - 28.6%)。2013年,这两个百分比分别显著增至24.9%和40.0%(P < 0.05)。5年期间THC浓度中位数在5.2至6.3纳克/毫升之间,个别浓度高达90纳克/毫升。在这5年期间,平均56%的案件THC浓度达到或超过5纳克/毫升。在提交检测的同一群涉嫌酒驾者中,酒精及大多数其他药物的流行率在这相同的5年期间没有变化——大麻是唯一一种频率出现这种增长的药物。此外,在对数据进行标准化处理以考虑在此期间发生的实验室检测程序变化之后,这种观察到的增长仍然存在。未来需要开展研究以确定观察到的这种增长是否对撞车、重伤和/或交通死亡事故的发生率产生了任何影响。

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