Department of Psychology, Zhejiang Normal University, Jinhua, Zhejiang Province, PR China.
Department of Psychology, Zhejiang Normal University, Jinhua, Zhejiang Province, PR China.
Prog Neuropsychopharmacol Biol Psychiatry. 2015 Jan 2;56:142-8. doi: 10.1016/j.pnpbp.2014.08.016. Epub 2014 Sep 10.
This study examined how Internet gaming disorder (IGD) subjects modulating reward and risk at a neural level under a probability-discounting task with functional magnetic resonance imaging (fMRI). Behavioral and imaging data were collected from 19 IGD subjects (22.2 ± 3.08 years) and 21 healthy controls (HC, 22.8 ± 3.5 years). Behavior results showed that IGD subjects prefer the probabilistic options to fixed ones and were associated with shorter reaction time, when comparing to HC. The fMRI results revealed that IGD subjects show decreased activation in the inferior frontal gyrus and the precentral gyrus when choosing the probabilistic options than HC. Correlations were also calculated between behavioral performances and brain activities in relevant brain regions. Both of the behavioral performance and fMRI results indicate that people with IGD show impaired risk evaluation, which might be the reason why IGD subjects continue playing online games despite the risks of widely known negative consequence.
本研究使用功能磁共振成像（fMRI）技术，考察了网络成瘾障碍（IGD）患者在概率折扣任务中调节奖励和风险的神经机制。研究共纳入 19 名 IGD 患者（22.2±3.08 岁）和 21 名健康对照者（HC，22.8±3.5 岁），并采集了行为学和影像学数据。行为学结果表明，与 HC 相比，IGD 患者更喜欢概率选项而非固定选项，且做出选择的反应时间更短。fMRI 结果显示，与 HC 相比，IGD 患者在选择概率选项时，额下回和中央前回的激活减弱。同时，还对相关脑区的行为表现和脑活动之间进行了相关性分析。行为学和 fMRI 结果均表明，IGD 患者的风险评估受损，这可能是 IGD 患者明知存在广为人知的负面后果仍继续玩网络游戏的原因。
