Wang L, Wu L, Lin X, Zhang Y, Zhou H, Du X, Dong G
Department of Psychology, Zhejiang Normal University, 688 Yingbin Road, Jinhua, Zhejiang Province 321004, PR China.
Department of Psychology, University of Konstanz, Konstanz, Germany.
Eur Psychiatry. 2016 Apr;34:36-42. doi: 10.1016/j.eurpsy.2016.01.2424. Epub 2016 Feb 27.
The present study identified the neural mechanism of risky decision-making in Internet gaming disorder (IGD) under a probability discounting task.
Independent component analysis was used on the functional magnetic resonance imaging data from 19 IGD subjects (22.2 ± 3.08 years) and 21 healthy controls (HC, 22.8 ± 3.5 years).
For the behavioral results, IGD subjects prefer the risky to the fixed options and showed shorter reaction time compared to HC. For the imaging results, the IGD subjects showed higher task-related activity in default mode network (DMN) and less engagement in the executive control network (ECN) than HC when making the risky decisions. Also, we found the activities of DMN correlate negatively with the reaction time and the ECN correlate positively with the probability discounting rates.
The results suggest that people with IGD show altered modulation in DMN and deficit in executive control function, which might be the reason for why the IGD subjects continue to play online games despite the potential negative consequences.
本研究确定了在概率折扣任务下网络游戏障碍（IGD）中风险决策的神经机制。
对19名IGD受试者（22.2±3.08岁）和21名健康对照者（HC，22.8±3.5岁）的功能磁共振成像数据进行独立成分分析。
行为结果方面，与HC相比，IGD受试者更喜欢风险选项而非固定选项，且反应时间更短。成像结果方面，在做出风险决策时，与HC相比，IGD受试者在默认模式网络（DMN）中表现出更高的任务相关活动，而在执行控制网络（ECN）中的参与度更低。此外，我们发现DMN的活动与反应时间呈负相关，ECN的活动与概率折扣率呈正相关。
结果表明，IGD患者在DMN中表现出改变的调节，执行控制功能存在缺陷，这可能是IGD受试者尽管存在潜在负面后果仍继续玩网络游戏的原因。
