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慢性乙型肝炎病毒合并感染与赞比亚感染艾滋病毒的成年人的肾功能损害有关。

Chronic hepatitis B virus coinfection is associated with renal impairment among Zambian HIV-infected adults.

作者信息

Mweemba Aggrey, Zanolini Arianna, Mulenga Lloyd, Emge Drew, Chi Benjamin H, Wandeler Gilles, Vinikoor Michael J

机构信息

Department of Medicine, University of Zambia University Teaching Hospital, Lusaka, Zambia.

Department of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill Centre for Infectious Disease Research in Zambia, Lusaka.

出版信息

Clin Infect Dis. 2014 Dec 15;59(12):1757-60. doi: 10.1093/cid/ciu734. Epub 2014 Sep 16.

DOI:10.1093/cid/ciu734
PMID:25228705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4311179/
Abstract

Among 6789 HIV-infected Zambian adults screened for hepatitis B virus (HBV) coinfection, estimated glomerular filtration rate (eGFR) was 50-90 mL/minute/1.73 m(2) in 17.6% and <50 mL/minute/1.73 m(2) in 2.5%. Human immunodeficiency virus/HBV coinfection was associated with eGFR <50 mL/minute/1.73 m(2) (adjusted odds ratio, 1.96 [95% confidence interval, 1.34-2.86]), adjusted for age, sex, CD4(+) count, and World Health Organization disease stage.

摘要

在6789名接受乙肝病毒（HBV）合并感染筛查的赞比亚成年HIV感染者中，估算肾小球滤过率（eGFR）为50 - 90毫升/分钟/1.73平方米的占17.6%，低于50毫升/分钟/1.73平方米的占2.5%。人类免疫缺陷病毒/乙肝病毒合并感染与eGFR低于50毫升/分钟/1.73平方米相关（校正比值比为1.96 [95%置信区间为1.34 - 2.86]），校正了年龄、性别、CD4+细胞计数和世界卫生组织疾病分期。

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