Mourya Devendra T, Yadav Pragya D, Shete Anita, Majumdar Triparna D, Kanani Amit, Kapadia Dhirendra, Chandra Vartika, Kachhiapatel Anantdevesh J, Joshi Pravinchandra T, Upadhyay Kamalesh J, Dave Paresh, Raval Dinkar
1 Maximum Containment Laboratory, Microbial Containment Complex, National Institute of Virology , Pune, Maharashtra, India .
Vector Borne Zoonotic Dis. 2014 Sep;14(9):690-2. doi: 10.1089/vbz.2014.1586.
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease that causes a fatal hemorrhagic illness in humans. This disease is asymptomatic in animals. CCHF was first confirmed in a nosocomial outbreak in 2011 in Gujarat State. Another notifiable outbreak occurred in July, 2013, in Karyana Village, Amreli district, Gujarat State. Anti-CCHF virus (CCHFV) immunoglobulin G (IgG) antibodies were detected in domestic animals from the adjoining villages of the affected area, indicating a considerable amount of positivity against domestic animals. The present serosurvey was carried out to determine the prevalence of CCHFV among bovine, sheep, and goat populations from 15 districts of Gujarat State, India. A total of 1226 serum samples from domestic animals were screened for IgG antibodies using a CCHF animal IgG enzyme-linked immunosorbent assay (ELISA) kit from the Centers for Disease Control and Prevention. Antibodies were detected in all the 15 districts surveyed; with positivity of 12.09%, 41.21%, and 33.62% in bovine, sheep, and goat respectively. This necessitates the surveillance of CCHFV IgG antibodies in animals and hemorrhagic fever cases in human.
克里米亚-刚果出血热（CCHF）是一种由蜱传播的病毒性疾病，可导致人类患上致命的出血性疾病。这种疾病在动物中无症状。CCHF于2011年在古吉拉特邦的一次医院内暴发中首次得到确认。另一起应报告的疫情于2013年7月发生在古吉拉特邦阿姆雷利区的卡里亚纳村。在受影响地区毗邻村庄的家畜中检测到了抗CCHF病毒（CCHFV）免疫球蛋白G（IgG）抗体，表明家畜的阳性率相当高。本次血清学调查旨在确定印度古吉拉特邦15个区的牛、绵羊和山羊群体中CCHFV的流行情况。使用疾病控制和预防中心的CCHF动物IgG酶联免疫吸附测定（ELISA）试剂盒，对总共1226份家畜血清样本进行了IgG抗体筛查。在所有调查的15个区均检测到了抗体；牛、绵羊和山羊的阳性率分别为12.09%、41.21%和33.62%。这就需要对动物中的CCHFV IgG抗体和人类出血热病例进行监测。
