Lindner Tobias, Krüger Christine, Kasch Cornelius, Finze Susanne, Steens Wolfram, Mittelmeier Wolfram, Skripitz Ralf
Department of Orthopaedics, University Medicine Rostock, 18057 Rostock, Germany.
Department of Orthopaedics, University Medicine Rostock, 18057 Rostock, Germany ; Orthopädisch-Neurochirugisches Zentrum, 45711 Datteln, Germany.
Open Orthop J. 2014 Sep 15;8:272-80. doi: 10.2174/1874325001408010272. eCollection 2014.
Numerous studies have shown reduction of periprosthetic bone mineral density (BMD) after hip replacement. The effect on the whole limb, however, is still unexplored. This study's objective was to analyse the postoperative development of BMD and muscle strength of the limb after total hip replacement (THR) and to determine links between these parameters.
55 patients, who underwent THR, were included. Depending on therapeutic indication, either an uncemented stem (Group A, n=30) or a cemented stem (Group B, n=25) has been implanted. In the limbs, the measurement of BMD using DEXA and the maximum isometric muscle strength, detected by a leg press, were undertaken preoperatively and after 3, 6 and 12 months.
A total of 12 patients (Group A: n = 6, Group B: n = 6) were excluded due to reasons which were not relevant to the study. So, the results refer to the data of 43 patients. In Group A (uncemented, n = 24), a significant decrease of BMD on the operated extremity was seen after 3, 6 and 12 months compared with preoperative values. Isometric muscle strength on the affected extremity increased significantly after 6 and 12 months. In Group B (cemented, n = 19), with a lower baseline compared to group A, an increase in BMD of the affected limb was seen postoperatively. This rise was significant after 12 months. With regard to the isometric muscle strength, a significant increase could be observed in this group after 6 and 12 months.
Analogous to postoperative reduction of periprosthetic bone density, a decrease of the entire limb BMD on the operated leg occurred after implantation of uncemented hip stems. In contrast, an increase in BMD was recorded for cemented stems. Regardless of the type of anchoring, a substantial increase in muscular strength could be observed postoperatively in both groups.
大量研究表明髋关节置换术后假体周围骨密度(BMD)会降低。然而,其对整个肢体的影响仍未得到探索。本研究的目的是分析全髋关节置换术(THR)后肢体骨密度和肌肉力量的术后变化,并确定这些参数之间的联系。
纳入55例行THR的患者。根据治疗指征,分别植入非骨水泥型假体柄(A组,n = 30)或骨水泥型假体柄(B组,n = 25)。术前以及术后3、6和12个月,使用双能X线吸收法(DEXA)测量肢体骨密度,并通过腿部推举检测最大等长肌肉力量。
共有12例患者(A组:n = 6,B组:n = 6)因与研究无关的原因被排除。因此,结果参考了43例患者的数据。在A组(非骨水泥型,n = 24)中,与术前值相比,术后3、6和12个月手术侧肢体的骨密度显著降低。患侧肢体的等长肌肉力量在术后6和12个月显著增加。在B组(骨水泥型,n = 19)中,与A组相比基线较低,术后患侧肢体骨密度增加。12个月后这种增加具有显著性。关于等长肌肉力量,该组在术后6和12个月可观察到显著增加。
与假体周围骨密度术后降低类似,植入非骨水泥型髋关节柄后,手术侧整个肢体的骨密度下降。相比之下,骨水泥型假体柄的骨密度有所增加。无论固定类型如何,两组术后肌肉力量均有显著增加。