兴奋-抑制平衡的形成：抑制进行倾听并改变其状态。
Formation of excitation-inhibition balance: inhibition listens and changes its tune.
作者信息
Tao Huizhong W, Li Ya-tang, Zhang Li I
机构信息
Zilkha Neurogenetic Institute, Los Angeles, CA 90089, USA; Department of Cell and Neurobiology, Zilkha Neurogenetic Institute, Los Angeles, CA 90089, USA.
Zilkha Neurogenetic Institute, Los Angeles, CA 90089, USA.
出版信息
Trends Neurosci. 2014 Oct;37(10):528-30. doi: 10.1016/j.tins.2014.09.001. Epub 2014 Sep 20.
Abstract
Recently, Xue, Atallah, and Scanziani reported that excitation/inhibition ratios across cortical pyramidal neurons are equalized by activity-dependent modulations of parvalbumin-neuron mediated feedforward inhibition. Their results raise questions about the developmental formation of this excitation-inhibition balance and the potential activity-dependent synaptic plasticity rules that mediate this process.
摘要
最近，薛、阿塔拉和斯坎齐亚尼报道，通过小白蛋白神经元介导的前馈抑制的活动依赖性调节，皮层锥体神经元的兴奋/抑制比率得以均衡。他们的研究结果引发了关于这种兴奋-抑制平衡的发育形成以及介导这一过程的潜在活动依赖性突触可塑性规则的问题。
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