Nakamura Yukio, Kamimura Mikio, Mukaiyama Keijiro, Ikegami Shota, Uchiyama Shigeharu, Kato Hiroyuki
Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.
Center of Osteoporosis and Spinal Disorders: Kamimura Orthopaedic Clinic, Matsumoto 399-0021, Japan.
Open Rheumatol J. 2014 Sep 12;8:20-3. doi: 10.2174/1874312901408010020. eCollection 2014.
Osteonecrosis (ON), subchondral insufficiency fracture (SIF), and rapidly destructive coxopathy (RDC) are considered to be clinically different disorders despite exhibiting several overlapping features. We encountered an elderly female patient with an atypical clinical course who was radiographically diagnosed as having osteoarthritis (OA), ON, SIF, and/or RDC over a long-term follow-up. In this case, radiographic diagnosis was apparently affected by the timing of imaging evaluation and was challenging because of radiographic overlap and atypical disease progression. The disorders of OA, SIF, ON, and RDC might share a similar pathophysiology.
尽管骨坏死（ON）、软骨下不全骨折（SIF）和快速破坏性关节病（RDC）表现出一些重叠特征，但它们在临床上被认为是不同的疾病。我们遇到了一位临床病程不典型的老年女性患者，在长期随访中，其影像学诊断为骨关节炎（OA）、ON、SIF和/或RDC。在这种情况下，影像学诊断显然受到成像评估时间的影响，并且由于影像学重叠和不典型的疾病进展而具有挑战性。OA、SIF、ON和RDC这些疾病可能具有相似的病理生理学。
