Khoshnevis Jalaluddin, Moradi Afshin, Azargashb Eznollah, Gholizade Barmak, Sobhiyeh Mohammad Reza
Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran ; Dept. of General and Vascular Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Cancer Prev. 2013 Winter;6(1):25-7.
The marginal length from main tumor in esophageal cancer is aconsiderable issue regarding surgical management and adjuvant treatment; so we decided to study the contractility effect on the proximal surgical margin after immersing it in10% buffered formalin as a fixative.
The proximal marginal length of ten sequential patients with esophageal cancer who underwent transhiatal esophagectomy were studied, on the operating table as fresh specimens, immediately after resection, and next 24, 48 and 72 hours after immersing in 10% buffered formalin.
The contraction continued through the day 3, the mean contractility after one day was about 27%, after two days was 33% and after three days was 38%.
This study shows how the proximal esophageal margin can vary by the time, after immersing in 10% buffered formalin and should be considered in every settings and reporting documents by pathologists.
食管癌主肿瘤的切缘长度是手术治疗和辅助治疗中一个相当重要的问题；因此，我们决定研究将食管癌近端手术切缘浸入10%中性福尔马林固定液后其收缩性的影响。
对10例连续接受经裂孔食管癌切除术的患者的近端切缘长度进行研究，在手术台上将切除后的新鲜标本立即进行测量，然后在浸入10%中性福尔马林后24、48和72小时再次测量。
收缩持续至第3天，1天后平均收缩率约为27%，2天后为33%，3天后为38%。
本研究表明，食管癌近端切缘浸入10%中性福尔马林后其长度会随时间变化，病理学家在所有情况下及报告文件中均应予以考虑。
