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免疫功能低下患者在摄入酸奶后发生鼻脑型卷枝毛霉感染。

Rhinocerebral Mucor circinelloides infection in immunocompromised patient following yogurt ingestion.

作者信息

Lazar Stephen P, Lukaszewicz Jennifer M, Persad Kamleish A, Reinhardt John F

出版信息

Del Med J. 2014 Aug;86(8):245-8.

Abstract

The purpose of this case report is to illustrate the cause of this patient's headache and sinus pain in the setting of a unique environmental exposure: the patient ingested yogurt only days before presentation. This particular brand of yogurt caused controversy in early September 2013 when the manufacturer voluntarily recalled all flavors. The yogurt was found to be contaminated with Mucor circinelloides. The recall was triggered by the FDA, after receiving many complaints from consumers affected by temporary gastrointestinal symptoms such as abdominal cramping, diarrhea, and nausea. This patient was diagnosed with Rhinocerebral mucormycosis through fungal culture of the affected area. He was specifically colonized with Mucor circinelloides, a variant that rarely causes disease in humans. According to a literature review, only eight cases of mucormycosis in adults caused by this strain were documented before 2009.

摘要

本病例报告的目的是阐明在一种独特的环境暴露情况下该患者头痛和鼻窦疼痛的病因

患者在就诊前几天食用了酸奶。这种特定品牌的酸奶在2013年9月初引发了争议,当时制造商主动召回了所有口味的产品。该酸奶被发现受到卷枝毛霉污染。此次召回是由美国食品药品监督管理局(FDA)触发的,此前FDA收到了许多受临时胃肠道症状(如腹部绞痛、腹泻和恶心)影响的消费者的投诉。通过对感染部位进行真菌培养,该患者被诊断为鼻脑型毛霉病。他感染的具体是卷枝毛霉,这是一种很少在人类中引起疾病的变体。根据文献综述,在2009年之前,仅有8例由该菌株引起的成人毛霉病病例被记录在案。

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