软组织中合并存在的肌上皮癌和肌上皮瘤：一例病例报告及文献复习
Combined myoepithelial carcinoma and myoepithelioma in soft tissue: a case report and review of the literature.
作者信息
Mahdi Youssef, Zouaidia Fouad, Zouhair Abdelilah, Azouz Mohamed, Znati Kaoutar, Jahid Ahmed, Berrada Mohamed Saleh, Bernoussi Zakiya, Mansouri Fatima, El Yaacoubi Moradh, Mahassini Najat
机构信息
Department of Pathology, Ibn Sina University Hospital, Rabat, Morocco.
出版信息
J Med Case Rep. 2014 Sep 24;8:317. doi: 10.1186/1752-1947-8-317.
INTRODUCTION
Soft tissue myoepithelial carcinoma and myoepithelioma are rare entities, part of myoepithelial tumors. They were incorporated into the World Health Organization classification of soft tissue tumors in 2002. Here we present an exceptional case of myoepithelial carcinoma and myoepithelioma association. To the best of our knowledge, such an association has never been reported in the literature.
CASE PRESENTATION
We report a case of myoepithelial carcinoma combined with myoepithelioma occurring in the soft tissue of the right forearm of an 84-year-old Arabian man. We describe the clinical, radiological and pathological features dominated by histological polymorphism. We will also describe the proposed histological criteria of malignancy and the major role of immunohistochemistry in positive and differential diagnosis. We finally mention the therapeutic arsenal available.
CONCLUSION
Through this work, we report that myoepithelioma of soft tissue can progress to malignant myoepithelioma.
引言
软组织肌上皮癌和肌上皮瘤是罕见的实体，属于肌上皮肿瘤的一部分。它们于2002年被纳入世界卫生组织软组织肿瘤分类。在此，我们报告一例肌上皮癌与肌上皮瘤关联的特殊病例。据我们所知，这种关联在文献中从未有过报道。
病例报告
我们报告一例84岁阿拉伯男性右前臂软组织中发生的肌上皮癌合并肌上皮瘤。我们描述了以组织学多形性为主的临床、放射学和病理学特征。我们还将描述提出的恶性组织学标准以及免疫组织化学在阳性和鉴别诊断中的主要作用。我们最后提及可用的治疗手段。
结论
通过这项工作，我们报告软组织肌上皮瘤可进展为恶性肌上皮瘤。
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