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足临泣穴针刺对减轻酒精依赖患者酒瘾的作用:一项随机安慰剂对照试验。

Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial.

作者信息

Lee Jin-Seong, Kim Sung-Gon, Jung Taek-Geun, Jung Woo Young, Kim Seong-Yeon

机构信息

Department of Psychiatry, Pusan National University Yangsan Hospital, Yangsan, Gyeongnam, 626-770, South Korea.

出版信息

Chin J Integr Med. 2015 Apr;21(4):307-11. doi: 10.1007/s11655-014-1851-1. Epub 2014 Sep 24.

DOI:10.1007/s11655-014-1851-1
PMID:25253549
Abstract

OBJECTIVE

To examine the effect of acupuncture on Zhubin (KI9) in reducing alcohol craving in alcohol-dependent patients.

METHODS

Twenty male alcohol-dependent patients were randomly assigned to two groups, a treatment group (10 cases, age 43.0±6.8 years) and a placebo group (10 cases, age 44.5±7.9 years). The treatment group was treated with real needle acupuncture on Zhubin (KI9) twice a week for 4 weeks, and the control group was treated with placebo needle acupuncture. Both groups were given acupuncture treatment using Park Sham Device (PSD). Alcohol craving was measured by the Visual Analogue Scale (VAS) before treatment to establish a baseline, and after 1, 2, and 4 weeks of treatment. Repeated measures ANOVA was used to determine the main and interaction effects of time and on the outcome measure (VAS).

RESULTS

There was a significant effect of time on VAS score (df=3, F=13.3, P<0.01). Main effect of group on VAS score was significant (df=1, F=10.9, P<0.01) and the time×group interaction was also significant (df=3, F=4.7, P<0.01).

CONCLUSIONS

Real-needle acupuncture therapy on Zhubin (KI9) showed effectiveness in reducing alcohol craving. These results strongly suggest the usefulness of acupuncture therapy on Zhubin (KI9) in preventing a relapse in alcohol dependent patients.

摘要

目的

探讨针刺足少阴肾经之筑宾穴(KI9)对减轻酒精依赖患者酒精渴望的作用。

方法

将20例男性酒精依赖患者随机分为两组,治疗组(10例,年龄43.0±6.8岁)和安慰剂组(10例,年龄44.5±7.9岁)。治疗组采用真针刺筑宾穴(KI9),每周2次,共4周,对照组采用假针刺。两组均使用朴氏假针法(PSD)进行针刺治疗。治疗前采用视觉模拟评分法(VAS)测量酒精渴望程度以建立基线,治疗1周、2周和4周后再次测量。采用重复测量方差分析来确定时间的主效应和交互效应以及对结局指标(VAS)的影响。

结果

时间对VAS评分有显著影响(自由度=3,F=13.3,P<0.01)。组间对VAS评分的主效应显著(自由度=1,F=10.9,P<0.01),时间×组间交互作用也显著(自由度=3,F=4.7,P<0.01)。

结论

针刺筑宾穴(KI9)真针疗法在减轻酒精渴望方面显示出有效性。这些结果有力地表明针刺筑宾穴(KI9)疗法在预防酒精依赖患者复发方面有用。

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