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高危急诊科患者中 Xpert Flu 快速 PCR 检测的评估。

Evaluation of the Xpert Flu rapid PCR assay in high-risk emergency department patients.

机构信息

Department of Emergency Medicine, Johns Hopkins University, Baltimore, Maryland, USA

Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA.

出版信息

J Clin Microbiol. 2014 Dec;52(12):4353-5. doi: 10.1128/JCM.02343-14. Epub 2014 Sep 24.

DOI:10.1128/JCM.02343-14
PMID:25253792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4313313/
Abstract

We prospectively evaluated the performance of Cepheid's GeneXpert Xpert Flu assay in a target population of 281 adults presenting to the emergency department with an acute respiratory illness who met Centers for Disease Control and Prevention (CDC) criteria for recommended antiviral treatment. Compared with the Prodesse ProFlu+ assay, Xpert Flu had an overall sensitivity of 95.3% and specificity of 99.2%.

摘要

我们前瞻性地评估了 Cepheid 公司的 GeneXpert Xpert Flu 检测在符合美国疾病控制与预防中心（CDC）推荐抗病毒治疗标准的 281 例急性呼吸道疾病就诊于急诊科的成年目标人群中的表现。与 Prodesse ProFlu+ 检测相比，Xpert Flu 的总敏感性为 95.3%，特异性为 99.2%。

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J Clin Microbiol. 2014 Feb;52(2):497-501. doi: 10.1128/JCM.02316-13. Epub 2013 Nov 27.
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New Microbiol. 2013 Oct;36(4):405-8. Epub 2013 Oct 1.
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J Infect Dis. 2013 Feb 15;207(4):553-63. doi: 10.1093/infdis/jis726. Epub 2012 Nov 29.
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J Virol Methods. 2012 Dec;186(1-2):137-40. doi: 10.1016/j.jviromet.2012.07.023. Epub 2012 Jul 25.
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