Yázigi Flavia, Carnide Filomena, Espanha Margarida, Sousa Miguel
Univ Lisboa, Fac Motricidade Humana, CIPER, LBMF, P-1499-002, Lisbon, Portugal.
Portuguese Institute of Rheumatology, Lisbon, Portugal.
Int J Rheum Dis. 2016 Jun;19(6):567-76. doi: 10.1111/1756-185X.12447. Epub 2014 Sep 24.
Self-report questionnaires are still considered to be a useful instrument for disease screening and for epidemiological studies. Few questionnaires have been developed for the purpose of screening for knee osteoarthritis (KOA). The aim of this study was to develop a KOA screening tool that is useful for health and exercise professionals who do not have access to advanced and costly diagnostic instruments.
This study comprised five steps: content validity, reliability, criterion validity, construct validity and responsiveness. Internal consistency was verified using Cronbach's alpha and the intraclass correlation coefficient (ICC). Reproducibility was analyzed using the ICC (1 week). Criterion validity was assessed by comparing the Knee OA Pre-Screening Questionnaire (KOPS) score with the Short Form (SF)-12, the Knee Injury and Osteoarthritis Outcome Scores questionnaire and the 6 min walk test. Construct validity was verified using the receiver operating characteristic (ROC) curve (American College of Rheumatology clinical criteria and X-ray). Responsiveness was analyzed over 3 months of an aquatic exercise program using the pooled effect size.
The overall KOPS score yielded a Cronbach's alpha of 0.747 and an ICC of 0.646. KOPS was considered reproducible (ICC: 0.895-0.992; Cronbach's alpha: 0.894-0.979). The ROC curve revealed a sensitivity of 86.96 and a specificity of 75.82. The KOPS demonstrated medium responsiveness in terms of the total score and the pain and symptoms components.
The KOPS questionnaire is valid for the purposes for which it was created, and its translation into English should be considered.
自我报告问卷仍被认为是疾病筛查和流行病学研究的有用工具。针对膝关节骨关节炎（KOA）筛查目的而开发的问卷很少。本研究的目的是开发一种KOA筛查工具，供无法使用先进且昂贵诊断仪器的健康和运动专业人员使用。
本研究包括五个步骤：内容效度、信度、效标效度、结构效度和反应度。使用Cronbach's α系数和组内相关系数（ICC）验证内部一致性。使用ICC（1周）分析可重复性。通过将膝关节骨关节炎预筛查问卷（KOPS）得分与简短健康调查问卷（SF-12）、膝关节损伤和骨关节炎疗效评分问卷以及6分钟步行试验进行比较来评估效标效度。使用受试者工作特征（ROC）曲线（美国风湿病学会临床标准和X线）验证结构效度。使用合并效应量分析在为期3个月的水上运动计划中的反应度。
KOPS总得分的Cronbach's α系数为0.747，ICC为0.646。KOPS被认为具有可重复性（ICC：0.895 - 0.992；Cronbach's α系数：0.894 - 0.979）。ROC曲线显示敏感性为86.96，特异性为75.82。KOPS在总分以及疼痛和症状分量表方面表现出中等反应度。
KOPS问卷对于其设计目的是有效的，应考虑将其翻译成英文。
