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辅助生殖后妊娠合并附件扭转——病例报告及文献综述

Adnexal Torsion in Pregnancy after Assisted Reproduction - Case Study and Review of the Literature.

作者信息

Spitzer D, Wirleitner B, Steiner H, Zech N H

机构信息

IVF Zentren Prof. Zech Salzburg, Salzburg, Austria.

IVF Zentren Prof. Zech Bregenz, Bregenz, Austria.

出版信息

Geburtshilfe Frauenheilkd. 2012 Aug;72(8):716-720. doi: 10.1055/s-0032-1315186.

Abstract

Aim of the study was to investigate the incidence, progress, management and outcome of adnexal torsion after controlled ovarian hyperstimulation in embryo transfer cycles. A retrospective analysis was done of 1007 patients of a private IVF centre. The literature on adnexal torsion is reviewed. In the literature, the incidence of adnexal torsion after assisted reproductive technologies (ART) is given as around 0.2 %. A significant increase of up to 33 % has been reported for cases with additional ovarian hyperstimulation syndrome (OHSS) and in pregnant women. In our retrospective analysis of 1007 women (incidence 0.46 %) with 1411 fresh embryo transfer cycles, we found an incidence of 0.35 % per embryo transfer. All adnexal torsions were treated by laparoscopic derotation to preserve fertility. All 5 cases with torsion were pregnant, 2 patients had mild OHSS. We recorded 3 term deliveries, 1 induced abortion for sirenomelia, and 1 missed abortion. Adnexal torsion must be kept in mind after hyperstimulation and embryo transfer, especially when pregnancy or OHSS is also present. With early diagnosis, it should be possible to preserve fertility using laparoscopic derotation.

摘要

本研究的目的是调查胚胎移植周期中控制性卵巢过度刺激后附件扭转的发生率、进展、处理及结局。对一家私立体外受精(IVF)中心的1007例患者进行了回顾性分析。并对附件扭转的相关文献进行了综述。文献报道辅助生殖技术(ART)后附件扭转的发生率约为0.2%。据报道,合并卵巢过度刺激综合征(OHSS)的病例及孕妇中,该发生率显著增加,高达33%。在我们对1007例女性(发生率0.46%)的1411个新鲜胚胎移植周期进行的回顾性分析中,我们发现每个胚胎移植的发生率为0.35%。所有附件扭转均通过腹腔镜复位术治疗以保留生育能力。所有5例扭转患者均已怀孕,2例患者有轻度OHSS。我们记录到3例足月分娩、1例因并腿畸形引产及1例稽留流产。在过度刺激和胚胎移植后,尤其是同时存在妊娠或OHSS时,必须考虑附件扭转。早期诊断后,通过腹腔镜复位术应该有可能保留生育能力。

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