Lin Xiao, Dong Guangheng, Wang Qiandong, Du Xiaoxia
Department of Psychology, Zhejiang Normal University, Jinhua, Zhejiang, PR China.
Department of Psychology, Zhejiang Normal University, Jinhua, Zhejiang, PR China.
Addict Behav. 2015 Jan;40:137-43. doi: 10.1016/j.addbeh.2014.09.010. Epub 2014 Sep 16.
Internet gaming addiction (IGA) is usually defined as the inability of an individual to control his/her use of the Internet with serious negative consequences. It is becoming a prevalent mental health concern around the world. To understand whether Internet gaming addiction contributes to cerebral structural changes, the present study examined the brain gray matter density and white matter density changes in participants suffering IGA using voxel-based morphometric analysis. Compared with the healthy controls (N=36, 22.2 ± 3.13 years), IGA participants (N=35, 22.28 ± 2.54 years) showed significant lower gray matter density in the bilateral inferior frontal gyrus, left cingulate gyrus, insula, right precuneus, and right hippocampus (all p<0.05). IGA participants also showed significant lower white matter density in the inferior frontal gyrus, insula, amygdala, and anterior cingulate than healthy controls (all p<0.05). Previous studies suggest that these brain regions are involved in decision-making, behavioral inhibition and emotional regulation. Current findings might provide insight in understanding the biological underpinnings of IGA.
网络成瘾（IGA）通常被定义为个人无法控制自己对网络的使用并产生严重负面后果。它正成为全球普遍关注的心理健康问题。为了了解网络成瘾是否会导致大脑结构变化，本研究使用基于体素的形态学分析，检查了患有网络成瘾的参与者的脑灰质密度和白质密度变化。与健康对照组（N = 36，22.2 ± 3.13岁）相比，网络成瘾参与者（N = 35，22.28 ± 2.54岁）在双侧额下回、左侧扣带回、脑岛、右侧楔前叶和右侧海马体中的灰质密度显著降低（所有p < 0.05）。网络成瘾参与者在额下回、脑岛、杏仁核和前扣带回中的白质密度也显著低于健康对照组（所有p < 0.05）。先前的研究表明，这些脑区参与决策、行为抑制和情绪调节。目前的研究结果可能有助于深入了解网络成瘾的生物学基础。
