Palmenberg Ann C, Gern James E
Institute for Molecular Virology, University of Wisconsin-Madison, 1525 Linden Drive, Madison, WI, 53706, USA,
Methods Mol Biol. 2015;1221:1-10. doi: 10.1007/978-1-4939-1571-2_1.
The historical classification of human rhinoviruses (RV) by serotyping has been replaced by a logical system of comparative sequencing. Given that strains must diverge within their capsid sequenced by a reasonable degree (>12-13 % pairwise base identities) before becoming immunologically distinct, the new nomenclature system makes allowances for the addition of new, future types, without compromising historical designations. Currently, three species, the RV-A, RV-B, and RV-C, are recognized. Of these, the RV-C, discovered in 2006, are the most unusual in terms of capsid structure, receptor use, and association with severe disease in children.
人类鼻病毒（RV）基于血清型的历史分类已被一个合理的比较测序系统所取代。鉴于毒株在其衣壳序列内必须有合理程度的差异（成对碱基同一性>12 - 13%）才会在免疫上变得不同，新的命名系统允许添加新的、未来的类型，同时不影响历史命名。目前，已识别出三个种，即RV - A、RV - B和RV - C。其中，2006年发现的RV - C在衣壳结构、受体使用以及与儿童严重疾病的关联方面最为特殊。
