Virkkala Jussi, Toppila Jussi, Maasilta Paula, Bachour Adel
Sleep Laboratory, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, 00250, Helsinki, Finland,
Sleep Breath. 2015 Sep;19(3):785-9. doi: 10.1007/s11325-014-1060-3. Epub 2014 Oct 1.
Recently, we have developed a simple method that uses two electro-oculography (EOG) electrodes for the automatic scoring of sleep-wake in normal subjects. In this study, we investigated the usefulness of this method on 284 consecutive patients referred for a suspicion of sleep apnea who underwent a polysomnography (PSG).
We applied the AASM 2007 scoring rules. A simple automatic sleep-wake classification algorithm based on 18-45 Hz beta power was applied to the calculated bipolar EOG channel and was compared to standard polysomnography. Epoch by epoch agreement was evaluated.
Eighteen patients were excluded due to poor EOG quality. One hundred fifty-eight males and 108 females were studied, their mean age was 48 (range 17-89) years, apnea-hypopnea index 13 (range 0-96) /h, BMI 29 (range 17-52) kg/m(2), and sleep efficiency 78 (range 0-98) %. The mean agreement in sleep-wake states between EOG and PSG was 85% and the Cohen's kappa was 0.56. Overall epoch-by-epoch agreement was 85%, and the Cohen's kappa was 0.57 with positive predictive value of 91% and negative predictive value of 65%.
The EOG method can be applied to patients referred for suspicion of sleep apnea to indicate the sleep-wake state.
最近，我们开发了一种简单的方法，该方法使用两个眼电图（EOG）电极对正常受试者的睡眠-觉醒进行自动评分。在本研究中，我们对284例因怀疑睡眠呼吸暂停而转诊并接受多导睡眠图（PSG）检查的连续患者，研究了该方法的实用性。
我们应用了美国睡眠医学学会（AASM）2007年的评分规则。将基于18 - 45Hzβ波功率的简单自动睡眠-觉醒分类算法应用于计算出的双极EOG通道，并与标准多导睡眠图进行比较。逐段评估一致性。
18例患者因EOG质量差被排除。研究了158名男性和108名女性，他们的平均年龄为48岁（范围17 - 89岁），呼吸暂停低通气指数为13次/小时（范围0 - 96次/小时），体重指数为29kg/m²（范围17 - 52kg/m²），睡眠效率为78%（范围0 - 98%）。EOG和PSG之间睡眠-觉醒状态的平均一致性为85%，Cohen's kappa系数为0.56。总体逐段一致性为85%，Cohen's kappa系数为0.57，阳性预测值为91%，阴性预测值为65%。
EOG方法可应用于因怀疑睡眠呼吸暂停而转诊的患者，以指示睡眠-觉醒状态。
