Nanobiotechnology Center, Markey Cancer Center, Lexington, KY USA ; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536 USA.
Biological Sciences, School of Environmental and Life Sciences, University of Newcastle, Callaghan, 2308 Australia.
Cell Biosci. 2014 Sep 16;4(1):54. doi: 10.1186/2045-3701-4-54. eCollection 2014.
Biomotors are extensively involved in biological processes including cell mitosis, bacterial binary fission, DNA replication, DNA repair, homologous recombination, Holliday junction resolution, RNA transcription, and viral genome packaging. Traditionally, they were classified into two categories including linear and rotation motors. In 2013, a third class of motor by revolution mechanism without rotation was discovered. In this issue of "Structure and mechanisms of nanomotors in the cells", four comprehensive reviews are published to address the latest advancements of the structure and motion mechanism of a variety of biomotors in archaea, animal viruses, bacteria, and bacteriophages.
生物马达广泛参与包括细胞有丝分裂、细菌二分分裂、DNA 复制、DNA 修复、同源重组、Holliday 连接分解、RNA 转录和病毒基因组包装在内的生物学过程。传统上，它们被分为线性和旋转马达两类。2013 年，人们发现了第三种旋转机制的旋转马达。在本期《细胞内纳米马达的结构与运动机制》中，发表了四篇综述文章，分别针对古菌、动物病毒、细菌和噬菌体中的各种生物马达的结构和运动机制的最新进展进行了介绍。
