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局部用皮质类固醇的全身性副作用。

Systemic side-effects of topical corticosteroids.

作者信息

Dhar Sandipan, Seth Joly, Parikh Deepak

机构信息

Department of Pediatric Dermatology, Institute of Child Health, Kolkata, India.

Department of Dermatology, Burdwan Medical College, Burdwan, West Bengal, India.

出版信息

Indian J Dermatol. 2014 Sep;59(5):460-4. doi: 10.4103/0019-5154.139874.

DOI:10.4103/0019-5154.139874
PMID:25284850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4171913/
Abstract

With the introduction of topical corticosteroids, a milestone has been achieved in dermatologic therapy; owing to its potent anti-inflammatory and ant proliferative effects, it became possible to treat some hitherto resistant dermatoses. But this magic drug can cause enough mischief if used inappropriately. Children are more susceptible to the systemic adverse effects because of enhanced percutaneous absorption through their tender skin. So, systemic side effects should be kept in mind while prescribing this therapeutically valuable topical medicament.

摘要

随着外用皮质类固醇的引入,皮肤病治疗领域取得了一个里程碑式的进展;由于其强大的抗炎和抗增殖作用,使得治疗一些此前难治的皮肤病成为可能。但如果使用不当,这种神奇的药物也会引发诸多问题。由于儿童娇嫩的皮肤经皮吸收增强,他们更容易受到全身不良反应的影响。因此,在开具这种具有治疗价值的外用药物时,应牢记全身副作用。

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J Hepatol. 2010 Jun;52(6):839-45. doi: 10.1016/j.jhep.2010.01.026. Epub 2010 Mar 15.
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