用替考拉宁治疗艰难梭菌相关性疾病。
Treatment of Clostridium difficile-associated disease with teicoplanin.
作者信息
de Lalla F, Privitera G, Rinaldi E, Ortisi G, Santoro D, Rizzardini G
机构信息
Department of Infectious Diseases, S. Anna Hospital, Como, Italy.
出版信息
Antimicrob Agents Chemother. 1989 Jul;33(7):1125-7. doi: 10.1128/AAC.33.7.1125.
Abstract
Forty-seven patients affected by Clostridium difficile-associated disease were treated orally with either vancomycin (patients hospitalized from February 1984 to February 1987) or teicoplanin (from March 1987 to December 1988). All patients given teicoplanin remained asymptomatic after discontinuation of treatment, and all but one were also cleared of C. difficile. In the vancomycin group, clinical symptoms recurred in 3 of 23 evaluable patients, and follow-up cultures were positive in another asymptomatic case.
摘要
47例艰难梭菌相关疾病患者分别接受口服万古霉素治疗（1984年2月至1987年2月住院患者）或替考拉宁治疗（1987年3月至1988年12月）。所有接受替考拉宁治疗的患者在停药后均无症状，除1例患者外，其余患者的艰难梭菌也均被清除。在万古霉素组中，23例可评估患者中有3例临床症状复发，另1例无症状患者的随访培养结果呈阳性。
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