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神经肿瘤学中的放射外科治疗选择:当前原则与未来机遇综述。第一部分:治疗策略。

Radiosurgical options in neuro-oncology: a review on current tenets and future opportunities. Part I: therapeutic strategies.

作者信息

Ganau Mario, Foroni Roberto Israel, Gerosa Massimo, Zivelonghi Emanuele, Longhi Michele, Nicolato Antonio

出版信息

Tumori. 2014 Jul-Aug;100(4):459-65. doi: 10.1700/1636.17912.

Abstract

Stereotactic radiosurgery can nowadays be considered not only as a potential adjuvant to surgical treatment of several neuro-oncological pathologies, including primary tumors and metastatic lesions, but in some cases also as a valuable alternative tailored option. In Part I of the review, we propose a dissertation focused on the different irradiation stereotactic radiosurgery techniques to date available for clinical indications more relevant to oncologists and oncologic surgeons, such as high-grade and low-grade gliomas, metastases and meningiomas. It is noteworthy that the most recent body of literature correlated with this topic shows that the therapeutic results presently achievable are revolutionizing the way patients are diagnosed and managed worldwide. As we sought to shed light on the current potentialities of stereotactic radiosurgery, we must consider that to exploit all the benefits provided by this shift in clinical practice, a profound awareness by all practitioners involved in the care of neoplastic patients is certainly warranted.

摘要

如今,立体定向放射外科不仅可被视为多种神经肿瘤疾病(包括原发性肿瘤和转移性病变)手术治疗的潜在辅助手段,而且在某些情况下还可作为一种有价值的个体化替代选择。在本综述的第一部分,我们提出一篇专题论文,重点关注迄今为止可用于临床适应症的不同立体定向放射外科照射技术,这些适应症与肿瘤学家和肿瘤外科医生更为相关,例如高级别和低级别胶质瘤、转移瘤和脑膜瘤。值得注意的是,与该主题相关的最新文献表明,目前可实现的治疗结果正在彻底改变全球患者的诊断和管理方式。当我们试图阐明立体定向放射外科的当前潜力时,我们必须认识到,为了充分利用临床实践中这一转变所带来的所有益处,所有参与肿瘤患者护理的从业者都必须有深刻的认识。

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