Ozdemir Ozhan, Sarı Mustafa Erkan, Sen Ertuğrul, Kurt Aslıhan, Ileri Ayşe Burce, Atalay Cemal Reşat
Department of Obstetrics and Gynecology, Ankara Numune Training and Research Hospital, Ankara, Turkey.
Department of Clinics Pathalogy, Ankara Numune Training and Research Hospital, Ankara, Turkey.
Niger Med J. 2014 Sep;55(5):432-7. doi: 10.4103/0300-1652.140391.
Sclerosing stromal tumours are rare benign ovarian neoplasms of the sex cord stromal that occur predominantly in the second and third decades of life. To date, 208 cases have been recorded in the literature. Most patients have menstrual irregularities and pelvic pain. Infertility and virilisation have also been described. In this article, histopathological features and differential diagnosis of the benign sclerosing stromal tumour were described together with the literature data. It is imperative to consider the differential diagnosis of a sclerozing stromal tumour of the ovary in a young woman with an ovarian tumour. A combination of morphological, immunohistochemical, radiological and clinical findings is needed in differentiating the tumour from thecoma, fibroma/fibrosarcoma, lipoid tumours and Krukenberg tumour.
硬化性间质瘤是一种罕见的性索间质卵巢良性肿瘤，主要发生于青少年期（第二个和第三个十年）。迄今为止，文献中已记录了208例病例。大多数患者有月经不规律和盆腔疼痛。也有不孕和男性化的报道。本文结合文献资料描述了良性硬化性间质瘤的组织病理学特征和鉴别诊断。对于患有卵巢肿瘤的年轻女性，必须考虑卵巢硬化性间质瘤的鉴别诊断。在将该肿瘤与卵泡膜瘤、纤维瘤/纤维肉瘤、类脂质肿瘤和库肯勃瘤相鉴别时，需要综合形态学、免疫组化、放射学和临床检查结果。
