Wu Yu-Tai, Cafiero-Chin Malinda, Marques Cathy
University of California, Berkeley, School of Optometry, Berkeley, California, USA.
Clin Exp Optom. 2015 Jan;98(1):25-30. doi: 10.1111/cxo.12200. Epub 2014 Oct 12.
Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is an uncommon disorder of ocular motility that possesses a unique spectrum of clinical findings, consisting of primary gaze exotropia, adduction impairment and nystagmus of the abducting eye. WEBINO is a variant of internuclear ophthalmoplegia (INO) sharing similar pathophysiology and aetiologies. Much of the literature published on internuclear ophthalmoplegia and its variants focuses on aetiology and pathophysiology, whereas there has been less information addressing prognosis and management. This review will provide current perspectives on the pathogenesis, prognosis and management of WEBINO syndrome.
外展神经麻痹性双眼核间性眼肌麻痹（WEBINO）是一种罕见的眼球运动障碍疾病，具有独特的一系列临床症状，包括原在位外斜视、内收障碍以及外展眼的眼球震颤。WEBINO是核间性眼肌麻痹（INO）的一种变体，具有相似的病理生理学和病因。关于核间性眼肌麻痹及其变体的许多文献都集中在病因和病理生理学方面，而关于预后和治疗的信息较少。本综述将提供关于WEBINO综合征发病机制、预后和治疗的当前观点。
