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评估军团菌对公众健康风险时存在的不确定性。

Uncertainties associated with assessing the public health risk from Legionella.

作者信息

Whiley Harriet, Keegan Alexandra, Fallowfield Howard, Ross Kirstin

机构信息

Health and the Environment, Flinders University Adelaide, SA, Australia.

South Australian Water Corporation Adelaide, SA, Australia.

出版信息

Front Microbiol. 2014 Sep 24;5:501. doi: 10.3389/fmicb.2014.00501. eCollection 2014.

Abstract

Legionella is an opportunistic pathogen of public health concern. Current regulatory and management guidelines for the control of this organism are informed by risk assessments. However, there are many unanswered questions and uncertainties regarding Legionella epidemiology, strain infectivity, infectious dose, and detection methods. This review follows the EnHealth Risk Assessment Framework, to examine the current information available regarding Legionella risk and discuss the uncertainties and assumptions. This review can be used as a tool for understanding the uncertainties associated with Legionella risk assessment. It also serves to highlight the areas of Legionella research that require future focus. Improvement of these uncertainties will provide information to enhance risk management practices for Legionella, potentially improving public health protection and reducing the economic costs by streamlining current management practices.

摘要

军团菌是一种引起公共卫生关注的机会性病原体。当前针对该病原体控制的监管和管理指南是基于风险评估制定的。然而,关于军团菌流行病学、菌株传染性、感染剂量和检测方法,仍存在许多未解答的问题和不确定性。本综述遵循EnHealth风险评估框架,审视当前有关军团菌风险的现有信息,并讨论不确定性和假设。本综述可作为一种工具,用于理解与军团菌风险评估相关的不确定性。它还旨在突出军团菌研究中未来需要重点关注的领域。改善这些不确定性将提供信息,以加强军团菌的风险管理实践,有可能通过简化当前管理实践来改善公共卫生保护并降低经济成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c65/4174118/c8e98c041fe9/fmicb-05-00501-g001.jpg

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