一种使用磁性纳米颗粒进行高精度远程温度探测的新方法。

Zhong Jing, Liu Wenzhong, Kong Li, Morais Paulo Cesar

1] School of Automation, Huazhong University of Science and Technology, Wuhan 430074, China [2] Key Laboratory of Image Information Processing and Intelligent Control, Huazhong University of Science and Technology, Wuhan 430074, China.

1] School of Automation, Huazhong University of Science and Technology, Wuhan 430074, China [2] Universidade de Brasília, Brasília DF 70910-900, Brazil.

Sci Rep. 2014 Oct 15;4:6338. doi: 10.1038/srep06338.

In this study, we report on a new approach for remote temperature probing that provides accuracy as good as 0.017°C (0.0055% accuracy) by measuring the magnetisation curve of magnetic nanoparticles. We included here the theoretical model construction and the inverse calculation method, and explored the impact caused by the temperature dependence of the saturation magnetisation and the applied magnetic field range. The reported results are of great significance in the establishment of safer protocols for the hyperthermia therapy and for the thermal assisted drug delivery technology. Likewise, our approach potentially impacts basic science as it provides a robust thermodynamic tool for noninvasive investigation of cell metabolism.

在本研究中，我们报告了一种用于远程温度探测的新方法，该方法通过测量磁性纳米颗粒的磁化曲线，可实现高达0.017°C的精度（精度为0.0055%）。我们在此纳入了理论模型构建和反演计算方法，并探讨了饱和磁化强度的温度依赖性和外加磁场范围所产生的影响。所报道的结果对于建立更安全的热疗方案和热辅助药物递送技术具有重要意义。同样，我们的方法可能会对基础科学产生影响，因为它为细胞代谢的无创研究提供了一种强大的热力学工具。