Zhang Wandi, Haskins Christopher W, Yang Yang, Dai Mingji
Department of Chemistry and Center for Cancer Research, Purdue University, 720 Clinic Drive, West Lafayette, IN 47907, USA.
Org Biomol Chem. 2014 Dec 7;12(45):9109-12. doi: 10.1039/c4ob01825g.
Palladium-catalyzed synthesis of nitriles from amides has been described. Two similar, but complementary reaction conditions have been identified to convert various amides including α,β,γ,δ-unsaturated amides, cinnamides, aromatic amides and alkyl amides to the corresponding nitriles in good to excellent yield.
已报道了钯催化酰胺合成腈的方法。现已确定两种相似但互补的反应条件，可将包括α,β,γ,δ-不饱和酰胺、肉桂酰胺、芳族酰胺和烷基酰胺在内的各种酰胺以良好至优异的产率转化为相应的腈。
