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德国疾病负担趋势:全球疾病负担研究的结果、影响及局限性

Trends in disease burden in Germany: results, implications and limitations of the Global Burden of Disease study.

作者信息

Plass Dietrich, Vos Theo, Hornberg Claudia, Scheidt-Nave Christa, Zeeb Hajo, Krämer Alexander

机构信息

Bielefeld University, Working Group 2, Department of Public Health Medicine, Bielefeld, Institute for Health Metrics and Evaluation, Seattle, USA, Bielefeld University, Working Group 7, Department of Environment and Health, Bielefeld, Department of Epidemiology and Health Monitoring of the Robert Koch Institute, Berlin, Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH, The Department of Prevention and Evaluation, Bremen.

出版信息

Dtsch Arztebl Int. 2014 Sep 19;111(38):629-38. doi: 10.3238/arztebl.2014.0629.

Abstract

BACKGROUND

The Global Burden of Disease (GBD) study is designed to give a comprehensive and standardized assessment of the health of populations around the world. It measures the burden of disease by considering years of life lost due to premature death as well as years lived with disability. The findings enable the identification of secular trends and disparities between countries and can serve as a basis for decision-making in health policy.

METHOD

In cooperation with the authors of the GBD study, we summarize the key methods used to assess the burden of disease in terms of disability-adjusted life years (DALYs). We present findings that specifically pertain to Germany, drawn from freely available data of the most recent round of analysis for the years 1990 and 2010.

RESULTS

According to the GBD study, life expectancy in Germany rose from 75.4 years in 1990 to 80.2 years in 2010. Ischemic heart disease and back pain caused the largest number of DALYs lost (2.5 million and 2.1 million, respectively). Over the period of the study, the absolute number of DALYs due to ischemic heart disease dropped by 33%, while the number of DALYs due to low back pain rose by 11%. Nutrition-related risks ranked first among all risk factors considered, accounting for 13.8% of total DALYs, followed by high blood pressure and high body-mass index, accounting for 10.9% each.

CONCLUSION

In Germany, important changes have been seen over time in the burden of disease attributable to different chronic diseases. Some of these changes reflect the successful interventions of the past, while others indicate a need for new action. The data from Germany that went into the GBD study must be systematically assessed and supplemented by further data relating to questions of specific relevance in this country.

摘要

背景

全球疾病负担(GBD)研究旨在对世界各地人群的健康状况进行全面、标准化的评估。该研究通过考虑因过早死亡导致的生命年损失以及带病生存年数来衡量疾病负担。这些研究结果有助于识别长期趋势以及各国之间的差异,并可为卫生政策决策提供依据。

方法

我们与GBD研究的作者合作,总结了用于以伤残调整生命年(DALYs)评估疾病负担的关键方法。我们呈现了从1990年和2010年最新一轮分析的免费可得数据中得出的、与德国具体相关的研究结果。

结果

根据GBD研究,德国的预期寿命从1990年的75.4岁增至2010年的80.2岁。缺血性心脏病和背痛导致的伤残调整生命年损失最多(分别为250万和210万)。在研究期间,因缺血性心脏病导致的伤残调整生命年绝对数下降了33%,而因腰痛导致的伤残调整生命年数上升了11%。在所有考虑的风险因素中,与营养相关的风险位居榜首,占总伤残调整生命年的13.8%,其次是高血压和高体重指数,各占10.9%。

结论

在德国,不同慢性病所致疾病负担随时间推移发生了重要变化。其中一些变化反映了过去成功的干预措施,而另一些则表明需要采取新行动。纳入GBD研究的德国数据必须得到系统评估,并辅以与该国具体相关问题的进一步数据。

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