Tandon Vishal R, Sharma Sudhaa, Mahajan Shagun, Raina Kaplia, Mahajan Annil, Khajuria Vijay, Gillani Zahid
Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
Department of Obstetrics and Gynaecology, Government Medical College, Jammu, Jammu and Kashmir, India.
J Midlife Health. 2014 Jul;5(3):121-5. doi: 10.4103/0976-7800.141188.
To evaluate prevalence of Vitamin D deficiency and establish any correlation between diabetes and vitamin D deficiency among postmenopausal women.
The 25-hydroxy vitamin D [25 (OH) D] concentrations were measured by competitive in-vitro quantitative immunoassay. The subjects were classified as vitamin D-deficient, insufficient or sufficient on the basis of 25 (OH) D concentrations of < 20 ng/mL, 20-30 ng/mL or > 30 ng/mL respectively. The apparently normal postmenopausal women (PMW) were subjected to fasting blood sugar levels to analyse any correlation between vitamin D deficiency and diabetes.
Vitamin D deficiency was observed in 53.35% of the population, 19.48% had insufficiency and 26.83% had adequate Vitamin D levels. In 12.14% of the study population fasting blood glucose was > 110 mg/dl and rest of the subjects were between the normal range which is 70-110mg/dl. Correlation between raised blood sugar levels and Vitamin D deficiency among PMW was non-significant (P = 0.324).
High prevalence of vitamin D deficiency exists among apparently healthy Indian PMW. However, the current study failed to show any statistical correlation between vitamin D deficiency and existence of diabetes, which may be due to small sample size.
评估绝经后女性维生素D缺乏的患病率，并确定糖尿病与维生素D缺乏之间是否存在相关性。
采用竞争性体外定量免疫分析法测定25-羟基维生素D[25(OH)D]浓度。根据25(OH)D浓度分别<20 ng/mL、20-30 ng/mL或>30 ng/mL，将研究对象分为维生素D缺乏、不足或充足。对表面健康的绝经后女性(PMW)进行空腹血糖水平检测，以分析维生素D缺乏与糖尿病之间的相关性。
53.35%的研究对象存在维生素D缺乏，19.48%存在不足，26.83%维生素D水平充足。12.14%的研究对象空腹血糖>110 mg/dl，其余对象血糖在70-110mg/dl的正常范围内。绝经后女性血糖水平升高与维生素D缺乏之间的相关性不显著(P = 0.324)。
在表面健康的印度绝经后女性中，维生素D缺乏的患病率较高。然而，本研究未能显示维生素D缺乏与糖尿病存在之间的任何统计学相关性，这可能是由于样本量较小。
