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婴儿急性鼻窦炎的眼眶并发症:一项系统综述及病例报告

Orbital complications of acute sinusitis in infants: a systematic review and report of a case.

作者信息

Sharma Saurabh, Josephson Gary D

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of South Florida, Tampa.

Pediatric Otolaryngology-Head and Neck Surgery, Nemours Children's Clinic, Jacksonville, Florida.

出版信息

JAMA Otolaryngol Head Neck Surg. 2014 Nov;140(11):1070-3. doi: 10.1001/jamaoto.2014.2326.

Abstract

IMPORTANCE

Orbital infections from acute sinusitis are rare in neonates and infants and can lead to devastating complications. To our knowledge, no prior dedicated review exists for evaluation, treatment, and outcomes of orbital complications in this age group.

OBJECTIVE

To perform a systematic review over the past 50 years on the diagnosis and treatment of orbital complications secondary to acute sinusitis in neonates and infants and report a case.

EVIDENCE AND ACQUISITION

A systematic review of the literature was performed searching PubMed to collect all the pertinent case reports and series in the English language with subperiosteal orbital abscess (SPOA) or orbital abscess in neonates or infants (date range, 1959-2012).

RESULTS

Eleven cases of SPOA in infants were identified, including our current case. Ages ranged from 10 to 74 days. There were 6 female and 5 male infants. The right eye was affected in 5 cases, the left in 5, and both in 1. There was 1 mortality in this series for which surgical drainage was not performed. Staphylococcus aureus was the most common organism isolated in 9 of 11 cases. Seven of the cases had open surgical drainage, 2 had endoscopic procedures (including our case), and 1 had spontaneous rupture of the abscess.

CONCLUSIONS AND RELEVANCE

An orbital complication due to acute sinusitis is rare in infants and neonates. Drainage in this patient population appears to be paramount, since the only infant in this series who did not receive drainage had died. Modern telescopes and equipment have allowed endoscopic drainage to be a safe and effective surgical treatment in this age group.

摘要

重要性

急性鼻窦炎引起的眶内感染在新生儿和婴儿中较为罕见,但可导致严重并发症。据我们所知,此前尚无专门针对该年龄组眶内并发症的评估、治疗及预后的综述。

目的

对过去50年新生儿和婴儿急性鼻窦炎继发眶内并发症的诊断和治疗进行系统综述并报告1例病例。

证据获取

通过检索PubMed对文献进行系统综述,以收集所有英文的有关新生儿或婴儿骨膜下眶脓肿(SPOA)或眶脓肿的相关病例报告和系列研究(时间范围为1959 - 2012年)。

结果

共识别出11例婴儿SPOA病例,包括我们当前报道的病例。年龄范围为10至74天。其中6例为女婴,5例为男婴。右眼受累5例,左眼受累5例,双眼受累1例。该系列中有1例未进行手术引流的患儿死亡。金黄色葡萄球菌是11例中9例最常见的分离病原体。7例进行了开放手术引流,2例采用了内镜手术(包括我们报道的病例),1例脓肿自发破裂。

结论及意义

急性鼻窦炎引起的眶内并发症在婴儿和新生儿中罕见。对于该患者群体,引流似乎至关重要,因为该系列中唯一未接受引流的婴儿死亡。现代内镜及设备已使内镜引流成为该年龄组安全有效的手术治疗方法。

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