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金属有机分子笼:生化影响的应用。

Metal-organic molecular cages: applications of biochemical implications.

机构信息

Laboratory of Organometallics, Catalysis and Ordered Materials, State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Center for Chemical and Material Engineering, Wuhan University of Technology, Wuhan 430070, China.

出版信息

Chem Soc Rev. 2015 Jan 7;44(1):9-25. doi: 10.1039/c4cs00222a. Epub 2014 Oct 16.

DOI:10.1039/c4cs00222a
PMID:25319756
Abstract

New well-designed materials are highly demanded with the prospect of versatile properties, offering successful applications as alternates to conventional materials. Major new insights into metal-organic self-assembled structures assisting biochemical purposes have recently emerged. Metal-organic polyhedral cages are highlighted as new research materials to be used for therapeutic, sensing and imaging, purposes etc. This tutorial review covers achievements in the biochemical applications of these multinuclear complexes. Examples of their ability to aid the ionic transport, biomolecular sensing, imaging, and drug delivery are presented.

摘要

新型设计精良的材料备受追捧,有望兼具多种特性,可作为传统材料的替代品而得到成功应用。最近,人们对有助于生化应用的金属-有机自组装结构有了全新的认识。金属-有机多面体笼被视为新型研究材料,可用于治疗、传感和成像等目的。本综述教程涵盖了这些多核配合物在生化应用方面的研究进展。展示了它们在促进离子传输、生物分子传感、成像和药物输送方面的应用实例。

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