Nateghi Rostami M, Nikmanesh B, Haghi-Ashtiani M T, Monajemzadeh M, Douraghi M, Ghalavand Z, Kashi L
Department of Public Health, Faculty of Health, Qom University of Medical Sciences, Qom, Iran.
Department of Pathology, Children's Medical Center, Tehran University of Medical Sciences, No. 62, Dr. Gharib St., Keshavarz Blvd., Tehran, Iran.
J Parasit Dis. 2014 Dec;38(4):444-6. doi: 10.1007/s12639-013-0272-y. Epub 2013 Mar 7.
Persistent diarrhea is a major manifestation of Acquired Immunodeficiency Syndrome (AIDS) which might be more complicated in Human Immunodeficiency Virus (HIV) infected children especially those from developing countries. There are numerous reports showing the emergence of intestinal opportunistic coccidian parasites, mostly Cryptosporidium parvum and Isospora belli in HIV-infected individuals. The prevalence of isosporiasis is probably underestimated in developing countries because routinely not all HIV-infected patients are examined for the presence of this protozoan infection. Here we report a case of HIV-infected isosporiasis presenting with failure to thrive and persistent diarrhea. Since I. belli infection in children responds well to therapy with trimethoprim-sulfamethoxazole, isosporiasis should be considered as a treatable infection in AIDS, if it is detected at proper time.
持续性腹泻是获得性免疫缺陷综合征(艾滋病)的主要表现之一,在感染人类免疫缺陷病毒(HIV)的儿童中可能更为复杂,尤其是来自发展中国家的儿童。有大量报告显示,HIV感染者肠道出现机会性球虫寄生虫,主要是微小隐孢子虫和贝氏等孢球虫。在发展中国家,等孢球虫病的患病率可能被低估了,因为通常并非所有HIV感染患者都接受这种原生动物感染的检查。在此,我们报告一例感染HIV的等孢球虫病病例,该病例表现为发育不良和持续性腹泻。由于儿童贝氏等孢球虫感染对甲氧苄啶 - 磺胺甲恶唑治疗反应良好,如果能在适当时间检测到,等孢球虫病应被视为艾滋病中一种可治疗的感染。