Hulvershorn Leslie A, Cullen Kathryn R, Francis Michael, Westlund Mindy
Indiana University School of Medicine, Department of Psychiatry, Indianapolis, IN.
University of Minnesota, Department of Psychiatry, Minneapolis, MN.
Curr Behav Neurosci Rep. 2014 Sep 1;1(3):161-169. doi: 10.1007/s40473-014-0020-3.
Resting state functional magnetic imaging (fMRI) is a novel means to examine functional brain networks. It allows investigators to identify functional networks defined by distinct, spontaneous signal fluctuations. Resting state functional connectivity (RSFC) studies examining child and adolescent psychiatric disorders are being published with increasing frequency, despite concerns about the impact of motion on findings. Here we review important RSFC findings on typical brain development and recent publications of child and adolescent psychiatric disorders. We close with a summary of the major findings and current strengths and limitations of RSFC studies.
静息态功能磁共振成像(fMRI)是一种用于检查大脑功能网络的新型手段。它使研究人员能够识别由不同的自发信号波动所定义的功能网络。尽管人们担心运动对研究结果的影响,但关于儿童和青少年精神疾病的静息态功能连接(RSFC)研究的发表频率却越来越高。在此,我们回顾了关于典型大脑发育的重要RSFC研究结果以及儿童和青少年精神疾病的近期相关出版物。我们最后总结了主要研究结果以及RSFC研究当前的优势和局限性。